Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Sozialpädiatrisches Zentrum, Paediatric Endocrinology and Diabetology, Berlin, Germany.
Kinder- und Jugendarztpraxis, Witten, Germany.
Pediatr Diabetes. 2020 Sep;21(6):1050-1058. doi: 10.1111/pedi.13065. Epub 2020 Jul 8.
International guidelines recommend psychosocial care for children and adolescents with type 1 diabetes.
To assess psychological care in children and adolescents with type 1 diabetes in a real-world setting and to evaluate associations with metabolic outcome.
Delivery of psychological care, HbA1c, and rates of severe hypoglycemia and diabetic ketoacidosis (DKA) in children and adolescents with type 1 diabetes from 199 diabetes care centers participating in the German diabetes survey (DPV) were analyzed.
Overall, 12 326 out of 31 861 children with type 1 diabetes were supported by short-term or continued psychological care (CPC). Children with psychological care had higher HbA1c (8.0% vs 7.7%, P<.001) and higher rates of DKA (0.032 vs 0.021 per patient-year, P<.001) compared with children without psychological care. In age-, sex-, diabetes duration-, and migratory background-matched children, HbA1c stayed stable in children supported by CPC during follow-up (HbA1c 8.5% one year before psychological care started vs 8.4% after two years, P = 1.0), whereas HbA1c was lower but increased significantly by 0.3% in children without psychological care (HbA1c 7.5% vs 7.8% after two years, P <.001). Additional HbA1c-matching showed that the change in HbA1c during follow-up was not different between the groups, but the percentage of children with severe hypoglycemia decreased from 16.3% to 10.7% in children receiving CPC compared with children without psychological care (5.5% to 5.8%, P =.009).
In this real-world setting, psychological care was provided to children with higher HbA1c levels. CPC was associated with stable glycemic control and less frequent severe hypoglycemia during follow-up.
国际指南建议为 1 型糖尿病患儿和青少年提供心理社会关怀。
在真实环境中评估 1 型糖尿病患儿和青少年的心理关怀情况,并评估其与代谢结果的关系。
分析参加德国糖尿病调查(DPV)的 199 个糖尿病护理中心的 31861 例 1 型糖尿病儿童和青少年的心理关怀提供情况、HbA1c 以及严重低血糖和糖尿病酮症酸中毒(DKA)的发生率。
总体而言,31861 例 1 型糖尿病儿童中有 12326 例接受了短期或持续的心理关怀(CPC)。与未接受心理关怀的儿童相比,接受心理关怀的儿童 HbA1c 更高(8.0%比 7.7%,P<.001),DKA 发生率更高(0.032 比 0.021 患者年,P<.001)。在年龄、性别、糖尿病病程和移民背景匹配的儿童中,接受 CPC 支持的儿童在随访期间 HbA1c 保持稳定(CPC 开始前一年的 HbA1c 为 8.5%,两年后为 8.4%,P=1.0),而未接受心理关怀的儿童的 HbA1c 则较低,但显著升高了 0.3%(两年后 HbA1c 为 7.5%,P<.001)。进一步的 HbA1c 匹配显示,两组儿童在随访期间 HbA1c 的变化无差异,但接受 CPC 的儿童严重低血糖的发生率从 16.3%下降到 10.7%,而未接受心理关怀的儿童则从 5.5%上升到 5.8%(P=.009)。
在这种真实环境中,为 HbA1c 水平较高的儿童提供了心理关怀。CPC 与随访期间血糖控制稳定和严重低血糖发生频率降低有关。