Division of Urology, University of Utah, Salt Lake City, Utah.
Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana.
Neurourol Urodyn. 2020 Aug;39(6):1771-1780. doi: 10.1002/nau.24420. Epub 2020 Jun 7.
Evidence is sparse on the long-term outcomes of continent cutaneous ileocecocystoplasty (CCIC). We hypothesized that obesity, laparoscopic/robotic approach, and concomitant surgeries would affect morbidity after CCIC and aimed to evaluate the outcomes of CCIC in adults in a multicenter contemporary study.
We retrospectively reviewed the charts of adult patients from sites in the Neurogenic Bladder Research Group undergoing CCIC (2007-2017) who had at least 6 months of follow-up. We evaluated patient demographics, surgical details, 90-day complications, and follow-up surgeries. the Mann-Whitney U test was used to compare continuous variables and χ² and Fisher's Exact tests were used to compare categorical variables.
We included 114 patients with a median age of 41 years. The median postoperative length of stay was 8 days. At 3 months postoperatively, major complications occurred in 18 (15.8%), and 24 patients (21.1%) were readmitted. During a median follow-up of 40 months, 48 patients (42.1%) underwent 80 additional related surgeries. Twenty-three patients (20.2%) underwent at least one channel revision, most often due to obstruction (15, 13.2%) or incontinence (4, 3.5%). Of the channel revisions, 10 (8.8%) were major and 14 (12.3%) were minor. Eleven patients (9.6%) abandoned the catheterizable channel during the follow-up period. Obesity and laparoscopic/robotic surgical approach did not affect outcomes, though concomitant surgery was associated with a higher rate of follow-up surgeries.
In this contemporary multicenter series evaluating CCIC, we found that the short-term major complication rate was low, but many patients require follow-up surgeries, mostly related to the catheterizable channel.
关于皮氏回肠贮尿囊(CCIC)的长期结果的证据很少。我们假设肥胖、腹腔镜/机器人方法和伴随手术会影响 CCIC 后的发病率,并旨在通过一项多中心的当代研究评估成人 CCIC 的结果。
我们回顾性地审查了神经源性膀胱研究组(Neurogenic Bladder Research Group)各站点中接受 CCIC(2007-2017 年)的成年患者的病历,这些患者的随访时间至少为 6 个月。我们评估了患者的人口统计学、手术细节、90 天并发症和随访手术。使用 Mann-Whitney U 检验比较连续变量,使用 χ²和 Fisher's Exact 检验比较分类变量。
我们纳入了 114 名中位年龄为 41 岁的患者。术后中位住院时间为 8 天。术后 3 个月时,18 例(15.8%)发生重大并发症,24 例(21.1%)再次入院。在中位随访 40 个月期间,48 例(42.1%)患者进行了 80 次额外的相关手术。23 例(20.2%)患者至少进行了一次通道修正,最常见的原因是梗阻(15 例,13.2%)或失禁(4 例,3.5%)。在通道修正中,10 例(8.8%)为主要修正,14 例(12.3%)为次要修正。11 例(9.6%)患者在随访期间放弃了可插管通道。肥胖和腹腔镜/机器人手术方法并不影响结果,但伴随手术与更高的随访手术率相关。
在这项评估 CCIC 的当代多中心系列研究中,我们发现短期主要并发症发生率较低,但许多患者需要进行随访手术,主要与可插管通道有关。