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在过去的 10 年中,成人使用连续皮片回肠-结肠膀胱成形术的当代多中心结局:神经源性膀胱研究组的研究。

Contemporary multicenter outcomes of continent cutaneous ileocecocystoplasty in the adult population over a 10-year period: A Neurogenic Bladder Research Group study.

机构信息

Division of Urology, University of Utah, Salt Lake City, Utah.

Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana.

出版信息

Neurourol Urodyn. 2020 Aug;39(6):1771-1780. doi: 10.1002/nau.24420. Epub 2020 Jun 7.

Abstract

AIMS

Evidence is sparse on the long-term outcomes of continent cutaneous ileocecocystoplasty (CCIC). We hypothesized that obesity, laparoscopic/robotic approach, and concomitant surgeries would affect morbidity after CCIC and aimed to evaluate the outcomes of CCIC in adults in a multicenter contemporary study.

METHODS

We retrospectively reviewed the charts of adult patients from sites in the Neurogenic Bladder Research Group undergoing CCIC (2007-2017) who had at least 6 months of follow-up. We evaluated patient demographics, surgical details, 90-day complications, and follow-up surgeries. the Mann-Whitney U test was used to compare continuous variables and χ² and Fisher's Exact tests were used to compare categorical variables.

RESULTS

We included 114 patients with a median age of 41 years. The median postoperative length of stay was 8 days. At 3 months postoperatively, major complications occurred in 18 (15.8%), and 24 patients (21.1%) were readmitted. During a median follow-up of 40 months, 48 patients (42.1%) underwent 80 additional related surgeries. Twenty-three patients (20.2%) underwent at least one channel revision, most often due to obstruction (15, 13.2%) or incontinence (4, 3.5%). Of the channel revisions, 10 (8.8%) were major and 14 (12.3%) were minor. Eleven patients (9.6%) abandoned the catheterizable channel during the follow-up period. Obesity and laparoscopic/robotic surgical approach did not affect outcomes, though concomitant surgery was associated with a higher rate of follow-up surgeries.

CONCLUSIONS

In this contemporary multicenter series evaluating CCIC, we found that the short-term major complication rate was low, but many patients require follow-up surgeries, mostly related to the catheterizable channel.

摘要

目的

关于皮氏回肠贮尿囊(CCIC)的长期结果的证据很少。我们假设肥胖、腹腔镜/机器人方法和伴随手术会影响 CCIC 后的发病率,并旨在通过一项多中心的当代研究评估成人 CCIC 的结果。

方法

我们回顾性地审查了神经源性膀胱研究组(Neurogenic Bladder Research Group)各站点中接受 CCIC(2007-2017 年)的成年患者的病历,这些患者的随访时间至少为 6 个月。我们评估了患者的人口统计学、手术细节、90 天并发症和随访手术。使用 Mann-Whitney U 检验比较连续变量,使用 χ²和 Fisher's Exact 检验比较分类变量。

结果

我们纳入了 114 名中位年龄为 41 岁的患者。术后中位住院时间为 8 天。术后 3 个月时,18 例(15.8%)发生重大并发症,24 例(21.1%)再次入院。在中位随访 40 个月期间,48 例(42.1%)患者进行了 80 次额外的相关手术。23 例(20.2%)患者至少进行了一次通道修正,最常见的原因是梗阻(15 例,13.2%)或失禁(4 例,3.5%)。在通道修正中,10 例(8.8%)为主要修正,14 例(12.3%)为次要修正。11 例(9.6%)患者在随访期间放弃了可插管通道。肥胖和腹腔镜/机器人手术方法并不影响结果,但伴随手术与更高的随访手术率相关。

结论

在这项评估 CCIC 的当代多中心系列研究中,我们发现短期主要并发症发生率较低,但许多患者需要进行随访手术,主要与可插管通道有关。

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