Kumar Mayank, Rao Meenakshi, Elhence Poonam, Kaushal Darwin, Yadav Taruna
Department of Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Department of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
J Oral Maxillofac Pathol. 2020 Jan-Apr;24(1):164-167. doi: 10.4103/jomfp.JOMFP_13_20. Epub 2020 May 8.
Schwannomas are rare benign encapsulated neoplasms that usually do not arise in the nasal and oral cavities. Only about 25% of the schwannomas are located in the head-and-neck region. The preoperative diagnosis of schwannomas in the head-and-neck region is difficult, as they present with varied clinical manifestations and have nonspecific radiological findings, which can lead to a diagnostic dilemma. We report two cases of schwannomas, one in the nasal cavity and the other in the tongue, that were considered to be an infective lesion and malignant lesion respectively on clinical evaluation. The biopsy and subsequent histopathological examination led to the diagnosis of schwannoma. It is important to be aware of the unusual clinical manifestations of schwannomas and keep it in the differential diagnoses, even at relatively uncommon sites such as the nasal and oral cavities. Lesions that are suspected to be infectious lesions or malignant lesions on clinical and/or radiological evaluation can also be schwannomas. Unnecessary diagnostic evaluations and radical therapeutic measures can be avoided with early diagnosis.
施万细胞瘤是罕见的良性包膜肿瘤，通常不发生于鼻腔和口腔。只有约25%的施万细胞瘤位于头颈部区域。头颈部施万细胞瘤的术前诊断困难，因为它们临床表现多样且影像学表现不具特异性，这可能导致诊断困境。我们报告两例施万细胞瘤病例，一例位于鼻腔，另一例位于舌部，临床评估时分别被认为是感染性病变和恶性病变。活检及随后的组织病理学检查确诊为施万细胞瘤。重要的是要意识到施万细胞瘤不寻常的临床表现，并将其纳入鉴别诊断，即使是在鼻腔和口腔等相对不常见的部位。临床和/或影像学评估怀疑为感染性病变或恶性病变的病变也可能是施万细胞瘤。早期诊断可避免不必要的诊断评估和根治性治疗措施。
