Ardeleanu Valeriu, Sabina Radaschin Diana, Tatu Alin Laurentiu
Arestetic Plastic Surgery Clinic, 800098 Galați, Romania.
Faculty of Medicine, Doctoral School, Ovidius University, 900533 Constanța, Romania.
Exp Ther Med. 2020 Jul;20(1):52-55. doi: 10.3892/etm.2020.8529. Epub 2020 Feb 14.
Psoriasis is a common cutaneous disease that has major implications in the quality of life of the patient. It is characterised by a chronic course and in some subtypes, it can be life threatening. Many studies have focused on the pathogenesis concerning this disease therefore improving the therapeutic approaches. Phototherapy represents a well-known treatment option for psoriasis. The depletion of T cells mostly from the epidermis, after exposure to phototherapy, validates the role of this treatment. The 308 nm excimer laser has the ability to treat mild, moderate and even severe but localised psoriasis plaques and plays an important role in the treatment management of psoriasis. In this report, we present the case of a patient diagnosed with plaque psoriasis, resistant to topical ointments, successfully treated with the 308 nm excimer laser. Although further studies are still required to consider the 308 nm excimer laser as a first line therapy, its high response rates have significantly influenced the therapeutic approach in psoriasis.
银屑病是一种常见的皮肤病，对患者的生活质量有重大影响。其特点是病程慢性，在某些亚型中，可能危及生命。许多研究聚焦于该疾病的发病机制，从而改进治疗方法。光疗是一种众所周知的银屑病治疗选择。暴露于光疗后，主要从表皮中消耗T细胞，证实了这种治疗的作用。308纳米准分子激光有能力治疗轻度、中度甚至重度但局限的银屑病斑块，在银屑病的治疗管理中发挥重要作用。在本报告中，我们介绍了一名被诊断为斑块状银屑病的患者，对局部药膏耐药，成功接受308纳米准分子激光治疗的病例。尽管仍需要进一步研究将308纳米准分子激光视为一线治疗方法，但其高反应率已显著影响银屑病的治疗方法。
