Sandru Florica, Draghici Carmen-Cristina, Predescu Teodora, Magdalena Constantin Maria, Petca Răzvan-Cosmin, Constantin Traian, Petca Aida, Cristian Dumitraşcu Mihai
'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Dermatology, 'Elias' Emergency University Hospital, 011461 Bucharest, Romania.
Exp Ther Med. 2020 Jul;20(1):87-90. doi: 10.3892/etm.2020.8675. Epub 2020 Apr 22.
Regressive melanoma is a phenomenon characterized by partial or complete replacement of cutaneous melanoma by fibrotic structures as a result of local host immune response. The dermoscopic features include 'scar-like' depigmentation that can be described as hypopigmented to pigmented macules, pink macules, linear-irregular vessels, globular vessel pattern, hyperpigmented macular remnants, blue gray 'peppered' papular remnants and white transverse bands. Fully regressive melanoma is very rare, and, in majority of cases, the tumor is associated with metastases, so the prognosis is very poor due to this fact. Regressive melanomas are rare since it represents an advance stage of melanoma evolution. Their treatment requires a collaboration between the dermatologist and the oncologist in order to improve the quality of life of the patient and also the survival rate.
消退性黑色素瘤是一种由于局部宿主免疫反应导致皮肤黑色素瘤被纤维结构部分或完全替代的现象。皮肤镜特征包括“瘢痕样”色素脱失,可表现为色素减退至色素沉着斑、粉红色斑、线性不规则血管、球状血管形态、色素沉着斑残留、蓝灰色“点状”丘疹残留和白色横纹。完全消退性黑色素瘤非常罕见,并且在大多数情况下,肿瘤伴有转移,因此基于这一事实预后非常差。消退性黑色素瘤很罕见,因为它代表黑色素瘤演变的晚期阶段。其治疗需要皮肤科医生和肿瘤内科医生合作,以提高患者的生活质量和生存率。