Swain Charlotte E, Cherubini Giunio B, Mantis Panagiotis
Dick White Referrals, Six Mile Bottom, Cambridgeshire, United Kingdom.
Front Vet Sci. 2020 May 19;7:274. doi: 10.3389/fvets.2020.00274. eCollection 2020.
There is no available measuring protocol and reference range for the normal canine trigeminal nerve. This can be problematic in cases of suspected bilateral trigeminal neuropathy since contralateral nerves cannot be a usefully compared. Trigeminal nerves and brain measurements were retrospectively assessed via multiplanar reconstruction (MPR) of 3DT1 post-contrast MR sequences from 137 dogs with no signs or diagnosis of trigeminal disease. Direct measurements of vertical brain height (BH), trigeminal nerves transverse height (TTH) and trigeminal nerves width in dorsal reconstruction (TDW) were made in a plane immediately caudal to the foramen ovale and used to derive trigeminal nerve-to-brain (NB) ratios, including height-to-brain ratio (HBR) and width-to-brain ratio (WBR). HBR (0.09, IQR = 0.08-0.09) and WBR (0.10, IQR = 0.09-0.11) maintained more consistent values across the study population compared to direct measurements of TTH (3.72, IQR = 3.42-4.07) and TDW (4.35 +/- 0.63). Calculated normal reference intervals for HBR and WBR were 0.07-0.11 and 0.08-0.13, respectively and the largest NB ratios recorded in normal dogs were 0.13 and 0.14 for HBR and WBR, respectively. All measurements varied proportionally with weight, including HBR ( = 0.41, < 0.0001) and small dogs had a significantly smaller HBRs compared to medium ( = 0.0294), large ( < 0.0049) and giant dogs ( < ). Median HBR was the same across skull types (0.09), however analysis detected significantly smaller HBRs in brachycephalic compared to mesaticephalic dogs ( = 0.0494). In conclusion, trigeminal NB ratios may allow for accurate, objective assessment of the canine trigeminal nerves on MRI but further quantification of the effects of weight and skull type on suggested reference intervals is needed.
目前尚无针对正常犬三叉神经的可用测量方案和参考范围。在疑似双侧三叉神经病变的病例中，这可能会成为问题，因为无法对侧神经进行有效比较。对137只无三叉神经疾病体征或诊断的犬，通过对3D T1增强后磁共振序列进行多平面重建（MPR），回顾性评估三叉神经和脑部测量数据。在紧挨着卵圆孔尾侧的平面上，直接测量垂直脑高（BH）、三叉神经横向高度（TTH）和背侧重建时三叉神经宽度（TDW），并用于得出三叉神经与脑（NB）的比率，包括高度与脑比率（HBR）和宽度与脑比率（WBR）。与TTH（3.72，IQR = 3.42 - 4.07）和TDW（4.35 +/- 0.63）的直接测量值相比，HBR（0.09，IQR = 0.08 - 0.09）和WBR（0.10，IQR = 0.09 - 0.11）在整个研究群体中保持了更一致的值。HBR和WBR的计算正常参考区间分别为0.07 - 0.11和0.08 - 0.13，正常犬中记录到的最大NB比率，HBR和WBR分别为0.13和0.14。所有测量值均与体重成比例变化，包括HBR（ = 0.41， < 0.0001），与中型犬（ = 0.0294）、大型犬（ < 0.0049）和巨型犬（ < ）相比，小型犬的HBR明显更小。不同头骨类型的HBR中位数相同（0.09），然而，分析发现与中头型犬相比，短头型犬的HBR明显更小（ = 0.0494）。总之，三叉神经NB比率可能有助于在MRI上对犬三叉神经进行准确、客观的评估，但需要进一步量化体重和头骨类型对建议参考区间的影响。
