俄罗斯原发性开角型青光眼患者中CDKN2B-AS1基因五个多态性位点的等位基因、基因型和单倍型频率数据集。
Dataset of allele, genotype and haplotype frequencies of five polymorphisms CDKN2B-AS1 gene in Russian patients with primary open-angle glaucoma.
作者信息
Eliseeva Natalya, Ponomarenko Irina, Reshetnikov Evgeny, Polonikov Alexey, Batlutskaya Irina, Aristova Inna, Elykova Anna, Rudykh Natalya, Churnosov Mikhail
机构信息
Department of Medical Biological Disciplines, Belgorod State University, 308015 Belgorod, Russia.
Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, 305041 Kursk, Russia.
出版信息
Data Brief. 2020 May 18;31:105722. doi: 10.1016/j.dib.2020.105722. eCollection 2020 Aug.
Abstract
Data on the allele, genotype and haplotype frequencies of the five single nucleotide polymorphisms (SNPs) such as rs1063192, rs7865618, rs2157719, rs944800 and rs4977756 of the gene in Russian patients with primary open-angle glaucoma (POAG) are provided. These SNPs are found to be associated with the risk of POAG by genome-wide association studies (GWAS). The frequencies of alleles, genotypes and haplotypes of gene were present separately for entire group of patients, females and males, and may be used as reference data of Russian population.
摘要
提供了俄罗斯原发性开角型青光眼（POAG）患者中该基因的五个单核苷酸多态性（SNP），如rs1063192、rs7865618、rs2157719、rs944800和rs4977756的等位基因、基因型和单倍型频率数据。通过全基因组关联研究（GWAS）发现这些SNP与POAG风险相关。该基因的等位基因、基因型和单倍型频率分别按患者全组、女性和男性列出，可作为俄罗斯人群的参考数据。
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