Gunaseelan Vinusha, Parkin Patricia C, Wahi Gita, Birken Catherine S, Maguire Jonathon L, Macarthur Colin, Borkhoff Cornelia M
Division of Paediatric Medicine and the Paediatric Outcomes Research Team (PORT), Hospital for Sick Children, Toronto, Ontario, Canada.
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
BMJ Paediatr Open. 2020 Apr 6;4(1):e000635. doi: 10.1136/bmjpo-2020-000635. eCollection 2020.
This study aimed to evaluate the association between maternal ethnicity and iron deficiency (ID) in early childhood, and to evaluate whether infant feeding practices linked to ID differ between maternal ethnic groups.
This was a cross-sectional study of healthy children 1-3 years of age. Adjusted multivariable logistic regression analyses were used to evaluate the association between maternal ethnicity and ID (serum ferritin <12 µg/L) and the association between maternal ethnicity and five infant feeding practices (breastfeeding duration; bottle use beyond 15 months; current formula use; daily cow's milk intake >2 cups; meat consumption).
Of 1851 children included, 12.2% had ID. Compared with the European referent group, we found higher odds of ID among children of South Asian and West Asian/North African maternal ethnicities, and lower odds of ID among children of East Asian maternal ethnicity. Statistically significant covariates associated with higher odds of ID included longer breastfeeding duration and daily cow's milk intake >2 cups. Current infant formula use was associated with lower odds of ID. Children of South Asian maternal ethnicity had higher odds of bottle use beyond 15 months of age and lower odds of meat consumption.
We found increased odds of ID among children of South Asian and West Asian/Northern African maternal ethnicities. We found a higher odds of feeding practices linked to ID in children of South Asian maternal ethnicity, but not in children of West Asian/North African maternal ethnicity. Culturally tailored approaches to providing guidance to parents on healthy infant feeding practices may be important to prevent ID in early childhood.
NCT01869530.
本研究旨在评估母亲种族与幼儿缺铁（ID）之间的关联，并评估与ID相关的婴儿喂养方式在不同母亲种族群体中是否存在差异。
这是一项针对1至3岁健康儿童的横断面研究。采用调整后的多变量逻辑回归分析来评估母亲种族与ID（血清铁蛋白<12μg/L）之间的关联，以及母亲种族与五种婴儿喂养方式（母乳喂养持续时间；15个月后使用奶瓶；当前使用配方奶；每日牛奶摄入量>2杯；肉类消费）之间的关联。
在纳入的1851名儿童中，12.2%患有ID。与欧洲参照组相比，我们发现南亚和西亚/北非母亲种族的儿童患ID的几率更高，而东亚母亲种族的儿童患ID的几率更低。与ID几率较高相关的具有统计学意义的协变量包括母乳喂养持续时间较长和每日牛奶摄入量>2杯。当前使用婴儿配方奶与ID几率较低相关。南亚母亲种族的儿童在15个月龄后使用奶瓶的几率较高，而肉类消费的几率较低。
我们发现南亚和西亚/北非母亲种族的儿童患ID的几率增加。我们发现南亚母亲种族的儿童采用与ID相关的喂养方式的几率较高，但西亚/北非母亲种族的儿童并非如此。采取针对文化特点的方法为父母提供关于健康婴儿喂养方式的指导，对于预防幼儿期ID可能很重要。
NCT01869530。
