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电休克疗法(ECT)的有效性和安全性。

The effectiveness and safety of electroconvulsive therapy (ECT).

作者信息

Turek I S, Hanlon T E

出版信息

J Nerv Ment Dis. 1977 Jun;164(6):419-31. doi: 10.1097/00005053-197706000-00008.

DOI:10.1097/00005053-197706000-00008
PMID:325181
Abstract

Over the past several decades, psychopharmacological treatments in psychiatry have been subjected to intensive methodological scrutiny in the continual assessment of their efficacy and safety. Although one of the most dramatic and controversial therapeutic approaches in psychiatry, electroconvulsive therapy (ECT) has not received the same concentrated, systematic attention. Through a comprehensive literature search, the present authors have attempted to provide answers relating to the efficacy and the safety of conventional ECT and some of its more prominent variations. Although specific discernible trends are reported in the text, results of the survey are too disparate for a simplistic summary statement to be made regarding efficacy in all diagnostic categories. As with most somatic treatments in psychiatry, bilateral ECT does present some apparent risk, reduced but not entirely eliminated by precautionary techniques, which must be weighed against the possible benefits to be derived in a given case. Other variations of ECT offer promise of fewer side effects but must be accepted as standard clinical practice.

摘要

在过去几十年里,精神病学中的心理药物治疗在持续评估其疗效和安全性时,一直受到严格的方法学审查。尽管电休克疗法(ECT)是精神病学中最引人注目的且最具争议的治疗方法之一,但它并未得到同样集中、系统的关注。通过全面的文献检索,本文作者试图提供有关传统ECT及其一些更突出变体的疗效和安全性的答案。尽管文中报告了具体可辨别的趋势,但调查结果差异太大,无法就所有诊断类别的疗效做出简单的总结陈述。与精神病学中的大多数躯体治疗一样,双侧ECT确实存在一些明显风险,预防性技术虽能降低但不能完全消除这些风险,在特定病例中必须权衡这些风险与可能获得的益处。ECT的其他变体有望减少副作用,但必须被接受为标准临床实践。

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The effectiveness and safety of electroconvulsive therapy (ECT).电休克疗法(ECT)的有效性和安全性。
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[Perstimulus asystole during electroconvulsive therapy: Clinical case and critical literature review].[电休克治疗期间的刺激后心脏停搏:临床病例与文献综述]
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引用本文的文献

1
Effectiveness of short term acute electroconvulsive therapy at three Brazilian sites: an observational cohort study.巴西三个地点短期急性电休克治疗的有效性:一项观察性队列研究。
Sao Paulo Med J. 2025 Feb 24;143(2):e2023292. doi: 10.1590/1516-3180.2023.0292.R1.03072024. eCollection 2025.
2
Ect in neurological counditions.在神经学疾病中。
Indian J Psychiatry. 2002 Jul;44(3):228-39.
3
The electroconvulsive therapy controversy: evidence and ethics.电休克治疗争议:证据与伦理
Neuropsychol Rev. 2003 Dec;13(4):199-219. doi: 10.1023/b:nerv.0000009484.76564.58.
4
Anaesthesia for electroconvulsive therapy: a psychiatric viewpoint.
Can Anaesth Soc J. 1981 Mar;28(2):153-7. doi: 10.1007/BF03007260.
5
Enhanced 5-hydroxytryptamine-mediated behavioural responses in rats following repeated electroconvulsive shock: relevance to the mechanism of the antidepressive effect of electroconvulsive therapy.重复电休克后大鼠中5-羟色胺介导的行为反应增强:与电休克治疗抗抑郁作用机制的相关性
Psychopharmacology (Berl). 1979 Mar 22;61(2):167-70. doi: 10.1007/BF00426732.