随着时间推移，D-二聚体和C反应蛋白血液水平用于预测两名新冠肺炎患者的肺栓塞情况。
D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients.
作者信息
Becher Yael, Goldman Leonid, Schacham Nadav, Gringauz Irina, Justo Dan
机构信息
Geriatrics and Internal Medicine B Department, Sheba Medical Center, Ramat-Gan, Israel; Aff. to Sackler School of Medicine, Tel-Aviv University, Israel.
出版信息
Eur J Case Rep Intern Med. 2020 May 20;7(6):001725. doi: 10.12890/2020_001725. eCollection 2020.
UNLABELLED
The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.
LEARNING POINTS
The diagnosis of pulmonary embolism is challenging in COVID-19 patients since symptoms, signs and high D-dimer blood levels might be similar in both diseases.An increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.
未标注
对于有症状的新冠肺炎患者，肺栓塞的诊断具有挑战性，因为呼吸急促、胸痛、心动过速、呼吸急促、发热、氧饱和度降低和血液中D-二聚体水平升高可能是这两种疾病的共同特征。我们报告了两名新冠肺炎患者，由于血液中D-二聚体水平升高与C反应蛋白水平随时间下降之间存在差异，怀疑（并诊断）为肺栓塞。我们认为，随着时间推移，这两种生物标志物血液水平的相反变化可作为预测新冠肺炎患者肺栓塞的一种新方法。
学习要点
对于新冠肺炎患者，肺栓塞的诊断具有挑战性，因为两种疾病的症状、体征和血液中高D-二聚体水平可能相似。随着时间推移，血液中D-二聚体水平升高和C反应蛋白水平下降可作为预测新冠肺炎患者肺栓塞的一种新方法。
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