Department of Urology, West China Hospital, Sichuan University, Chengdu, China.
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Urol Int. 2020;104(11-12):960-967. doi: 10.1159/000506779. Epub 2020 Jun 11.
Inflammatory myofibroblastic tumors (IMTs) of the urinary system are relatively rare and often misdiagnosed. We aimed to summarize and analyze the clinical manifestations, imaging features, management, and follow-up of renal and bladder IMTs.
In this retrospective study, 22 patients with IMT pathologically verified between 2009 and 2018 were included. Epidemiologic, clinical, pathologic, and imaging findings were recorded. Tumor size, location, and shape were analyzed and summarized.
There were 22 patients with a median age of 45 years (range: 20-74), including 14 patients with renal IMT and 8 patients with bladder IMT, who met the eligibility criteria. In 21 patients, IMT appeared as a single lesion, whereas 1 patient showed bilateral renal lesions. Surgical resection was the sole therapy, and follow-up information was acquired from 13 individuals with no evidence of recurrence or metastasis. In our study, a slightly hypodense or isodense homogeneous tumor with a clear boundary was more often seen. On contrast-enhanced computed tomography (CT), they were often manifesting as a slightly heterogeneous enhancement.
The nature of IMTs might cause a lack of generalizability. However, it will be useful to know that there are various CT demonstrations of IMTs. CT images are useful for the detection, location, and characterization of urinary IMTs, which can help in better clinical decision-making and can also be an optimal imaging technique for follow-up.
泌尿系统炎性肌纤维母细胞瘤(IMT)相对少见,常被误诊。本研究旨在总结和分析肾脏和膀胱 IMT 的临床表现、影像学特征、处理方法和随访情况。
本回顾性研究纳入了 2009 年至 2018 年间经病理证实的 22 例 IMT 患者。记录了流行病学、临床、病理和影像学发现。分析和总结了肿瘤的大小、位置和形状。
符合纳入标准的 22 例患者的中位年龄为 45 岁(范围:20-74 岁),包括 14 例肾脏 IMT 和 8 例膀胱 IMT 患者。21 例患者的 IMT 表现为单个病灶,1 例患者表现为双侧肾脏病变。所有患者均接受了单纯手术切除治疗,13 例患者获得了随访资料,均未见复发或转移。在本研究中,我们观察到边界清晰的稍低密度或等密度均匀性肿瘤更为常见。在增强 CT 上,这些肿瘤通常表现为轻度不均匀强化。
IMT 的性质可能导致其缺乏普遍性。然而,了解 IMT 有多种 CT 表现是很有用的。CT 图像有助于检测、定位和描述泌尿系统 IMT,可以帮助做出更好的临床决策,也是随访的最佳影像学技术。