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膀胱炎性肌纤维母细胞瘤:计算机断层扫描特征

Inflammatory myofibroblastic tumor of the bladder: Computed tomographic features.

作者信息

Liang Pan, Zhu Bing-Bing, Ren Xiu-Chun, Gao Jian-Bo

机构信息

Department of Radiology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.

出版信息

Mol Clin Oncol. 2023 Mar 22;18(5):40. doi: 10.3892/mco.2023.2636. eCollection 2023 May.

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare tumor with intermediate biologic potential, in which lack of understanding often poses difficulties in preoperative diagnosis and treatment. The aim of the present study was to characterize the computed tomography (CT) features of the bladder IMT. The CT images of nine pathologically confirmed bladder IMT were retrospectively reviewed. All patients underwent both unenhanced CT and contrast-enhanced CT. The diameter, location, contour, growth pattern, margin, boundary, density and enhancement pattern of the lesions were assessed. The mean Ki67 value of an irregular blood clot was 18% and that of no blood clot was 12%. A total of eight (89%) patients had one tumor and 1 (11%) patient had multiple tumors. An endophytic growth pattern was observed in 4 (44%) patients, an exophytic growth pattern in 2 (22%) patients, and a mixed growth pattern in 3 (33%) patients. The tumor manifests morphologically as either polypoid (n=5), or cauliflower-like (n=1) soft-tissue mass with a wide base in the cavity, or a limited thick-walled (n=3). The tumor margins were smooth (n=8) or lobulated (n=1), and the tumor boundaries were either clear (n=7) or ill-defined (n=2). The lesions showed either ring-shaped (n=3) or heterogeneous (n=6). The polypoid and cauliflower-like soft-tissue mass showed a symmetrical change in the center of the lesion after enhancement. The bladder IMT is mostly a single polypoid nodule in the superior wall, mostly endophytic growth, with ring-haped enhancement and symmetrical change after enhancement as its characteristic manifestations.

摘要

炎性肌纤维母细胞瘤(IMT)是一种具有中等生物学潜能的罕见肿瘤,对其认识不足常常给术前诊断和治疗带来困难。本研究的目的是描述膀胱IMT的计算机断层扫描(CT)特征。回顾性分析了9例经病理证实的膀胱IMT的CT图像。所有患者均接受了平扫CT和增强CT检查。评估了病变的直径、位置、轮廓、生长方式、边缘、边界、密度和强化方式。不规则血凝块的平均Ki67值为18%,无血凝块的为12%。共有8例(89%)患者为单发肿瘤,1例(11%)患者为多发肿瘤。4例(44%)患者表现为内生性生长方式,2例(22%)患者为外生性生长方式,3例(33%)患者为混合性生长方式。肿瘤形态上表现为息肉样(n=5)、菜花状(n=1)软组织肿块,基底较宽位于腔内,或局限性厚壁(n=3)。肿瘤边缘光滑(n=8)或呈分叶状(n=1),肿瘤边界清晰(n=7)或不清(n=2)。病变表现为环形(n=3)或不均匀性(n=6)。息肉样和菜花状软组织肿块增强后病变中心呈对称性改变。膀胱IMT大多为上壁单个息肉样结节,多为内生性生长,以环形强化及增强后对称性改变为特征表现。

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本文引用的文献

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Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report.膀胱炎性肌纤维母细胞瘤:一例报告
J Endourol Case Rep. 2019 May 30;5(2):31-33. doi: 10.1089/cren.2018.0096. eCollection 2019.

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