糖尿病作为乳腺癌的一个风险因素。
Diabetes as a Risk Factor for Breast Cancer.
作者信息
Eketunde Adenike O
机构信息
Public Health, University of Massachusetts Lowell, Lowell, USA.
出版信息
Cureus. 2020 May 7;12(5):e8010. doi: 10.7759/cureus.8010.
Abstract
Diabetes is one of the most important chronic conditions worldwide, and breast cancer is the most prevalent cancer in women worldwide. Several types of research have been conducted to ascertain the link between diabetes and its potential for increasing the risk of breast cancer. This research aims to determine the relationship between diabetes and breast cancer; patients with diabetes have a higher risk than the general population of developing cancer, and diabetes patients have a higher incidence and mortality of breast cancer. This research also reviewed the relationship between cytokines, the mitogenic effect of insulin-like growth factors, and breast cells. The review includes searching the PubMed database using the keywords "diabetes," "breast cancer," "risk factor," and "premenopausal." The search returned 53 articles used for review of this article.
摘要
糖尿病是全球最重要的慢性病之一，而乳腺癌是全球女性中最常见的癌症。已经开展了几种类型的研究来确定糖尿病与其增加患乳腺癌风险可能性之间的联系。本研究旨在确定糖尿病与乳腺癌之间的关系；糖尿病患者患癌症的风险高于普通人群，且糖尿病患者患乳腺癌的发病率和死亡率更高。本研究还综述了细胞因子、胰岛素样生长因子的促有丝分裂作用与乳腺细胞之间的关系。该综述包括使用关键词“糖尿病”“乳腺癌”“风险因素”和“绝经前”搜索PubMed数据库。搜索结果返回了53篇用于本文综述的文章。
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