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韩国消费的渔业产品中重金属的暴露评估和安全摄入指南。

Exposure assessment and safe intake guidelines for heavy metals in consumed fishery products in the Republic of Korea.

机构信息

Noeun Inspection Office for Agricultural, Fishery and Livestock Products, Daejeon Metropolitan City Institute of Health and Environment, Yuseong-gu, Daejeon, 34146, Republic of Korea.

Food Contaminants Division, Food Safety Evaluation Department, Ministry of Food and Drug Safety, National Food and Drug Safety Evaluation, Osong, Cheongju, 28159, Republic of Korea.

出版信息

Environ Sci Pollut Res Int. 2020 Sep;27(26):33042-33051. doi: 10.1007/s11356-020-09624-0. Epub 2020 Jun 11.

DOI:10.1007/s11356-020-09624-0
PMID:32529622
Abstract

Heavy metals in food are non-intentional pollutants such as lead (Pb), cadmium (Cd), and mercury (Hg). Pb, a neurotoxic substance, is classified as a possible carcinogen for humans (group 2B) by the International Agency for Research on Cancer (IARC) under the World Health Organization (WHO). Cd, a substance that causes kidney damage, is classified as a substance that causes human cancer (group 1). In this study, inductively coupled plasma atomic emission spectrometry (ICP-AES) and a mercury analyzer (MA) were used to identify the concentrations of heavy metals (Pb, Cd, Hg) in fishery products and to assess the effects of chronic human exposure to heavy metals via fisheries consumption. Food consumption data were obtained from the Korea National Health and Nutrition Examination Survey (KNHANES 2010-2015), and the mean exposure concentrations for Pb, Cd, and Hg were 0.0067 μg/kg bw/day, 1.1277 μg/kg bw/month, and 0.0872 μg/kg bw/week, respectively. Exposures to Pb, Cd, and Hg using the 95th percentile of the consumption data were 0.0183 μg/kg bw/day, 4.0230 μg/kg bw/month, and 0.2268 μg/kg bw/week, respectively, corresponding to 3, 16, and 6% of the human exposure safety standard. Safe guidelines for the intake of fishery products are proposed to reduce the exposure to and accumulation of heavy metals in humans.

摘要

食品中的重金属是非故意污染物,如铅(Pb)、镉(Cd)和汞(Hg)。国际癌症研究机构(IARC)下属的世界卫生组织(WHO)将 Pb 这种神经毒性物质列为可能的人类致癌物(2B 组)。Cd 是一种会导致肾脏损伤的物质,被列为人类致癌物(1 组)。在这项研究中,采用电感耦合等离子体原子发射光谱法(ICP-AES)和汞分析仪(MA)来确定渔业产品中重金属(Pb、Cd、Hg)的浓度,并评估人类通过食用渔业产品慢性暴露于重金属的影响。食物消费数据来自韩国国家健康和营养调查(KNHANES 2010-2015),Pb、Cd 和 Hg 的平均暴露浓度分别为 0.0067μg/kg bw/day、1.1277μg/kg bw/month 和 0.0872μg/kg bw/week。使用消费数据的第 95 百分位数进行暴露评估,Pb、Cd 和 Hg 的暴露量分别为 0.0183μg/kg bw/day、4.0230μg/kg bw/month 和 0.2268μg/kg bw/week,分别占人类暴露安全标准的 3%、16%和 6%。为了减少人类对重金属的暴露和积累,提出了安全食用水产品的指导方针。

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