Department of Surgery, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA.
Medical Doctoral School, Tulcea Emergency Hospital, IOSUD Titu Maiorescu University of Bucharest, Bucharest, Romania.
Ann Surg Oncol. 2021 Jan;28(1):131-132. doi: 10.1245/s10434-020-08715-z. Epub 2020 Jun 14.
When endoscopic options fail, laparoscopic pancreatic head-preserving duodenectomy (LPHPD) for benign duodenal lesions is a parenchymal sparing and safe alternative to a pancreaticoduodenectomy.1-3 LPHPD may be the optimal "amount" of surgery, because such lesions are at risk for undertreatment (partial endoscopic resection associated with recurrence) or overtreatment (Whipple associated with morbidity and loss of pancreatic parenchyma).4,5 PATIENT: A 80-year-old, healthy female patient was diagnosed endoscopically with two, flat, symptomatic adenomas (7-cm D2; 2-cm D3). She had no family history of polyposis. Germline testing, tumor markers, and colonoscopy did not show any abnormality.
With the patient in French position, a wide laparoscopic Kocherization was performed past IVC and aorta. Following prepyloric gastric transection, the entire duodenum was carefully dissected off the pancreas. After transection of the proximal jejunum, the reconstruction begins. A two-layer, duct-to-mucosa, ampullary-jejunal anastomosis and a type II Billroth gastrojejunostomy were performed.
LPHPD avoids under- or overtreatment of benign duodenal lesions unamenable to an endoscopic approach. If the stepwise approach described in this video is followed, LPHPD represents a safe and parenchymal-sparing alternative to pancreaticoduodenectomy for benign duodenal lesions with reduced morbidity.
当内镜治疗失败时,对于良性十二指肠病变,腹腔镜保留胰头十二指肠切除术(LPHPD)是一种比胰十二指肠切除术更能保留实质的安全替代方案。1-3 LPHPD 可能是最佳的“手术量”,因为这些病变存在治疗不足的风险(内镜下切除相关的复发)或过度治疗的风险(Whipple 相关的发病率和胰腺实质丧失)。4,5 患者:一位 80 岁健康的女性患者,经内镜诊断为两个平坦、有症状的腺瘤(7-cm D2;2-cm D3)。她没有家族性息肉病史。种系测试、肿瘤标志物和结肠镜检查均未发现异常。
患者取法国体位,行广泛的腹腔镜 Kocher 化术,越过 IVC 和主动脉。胃前壁切开后,小心地将整个十二指肠从胰腺上分离下来。近端空肠切断后,开始重建。行双层、胆管黏膜吻合和壶腹空肠吻合以及 II 型 Billroth 胃空肠吻合术。
LPHPD 避免了无法通过内镜治疗的良性十二指肠病变的治疗不足或过度治疗。如果按照本视频中描述的逐步方法进行操作,LPHPD 代表了一种安全且保留实质的替代方案,可用于治疗良性十二指肠病变,减少发病率。