Department of Cardiology, Osaka Medical College, Japan.
Medical Education Center, Osaka Medical College, Japan.
Intern Med. 2020 Sep 15;59(18):2275-2280. doi: 10.2169/internalmedicine.4524-20. Epub 2020 Jun 15.
We herein report a woman diagnosed with cardiac sarcoidosis (CS) based on the presence of epithelioid granulomas in non-cardiac organs and clinical findings including sustained ventricular tachycardia (VT) and cardiac dysfunction. She stopped oral corticosteroid after 4 years of treatment, and an abnormal myocardial uptake of fluorine-18 fluorodeoxyglucose and sustained VT recurred 3.5 years later. There is no consensus concerning whether or not corticosteroid therapy should be discontinued in the treatment of CS. As a relapse of sarcoidosis-related inflammation may be associated with life-threatening arrhythmia, some patients should continue corticosteroid therapy, even at low doses.
我们在此报告一例女性心脏结节病(CS)患者,其依据是非心脏器官存在上皮样肉芽肿和临床发现,包括持续性室性心动过速(VT)和心功能障碍。她在治疗 4 年后停止口服皮质类固醇,3.5 年后再次出现氟-18 氟脱氧葡萄糖摄取异常和持续性 VT。关于 CS 的治疗是否应停止皮质类固醇治疗,尚无共识。由于结节病相关炎症的复发可能与危及生命的心律失常有关,因此一些患者即使低剂量也应继续皮质类固醇治疗。