Chiao Joan Y, Li Shu-Chen, Turner Robert, Lee-Tauler Su Yeon
International Cultural Neuroscience Consortium, Highland Park, IL, USA.
Technische Universität Dresden, Dresden, Germany; Centre for Tactile Internet with Human-in-the-Loop, TU Dresden, Germany.
Neurosci Biobehav Rev. 2020 Sep;116:109-119. doi: 10.1016/j.neubiorev.2020.06.005. Epub 2020 Jun 12.
A comprehensive understanding of the basic molecular and cellular mechanisms of the brain is important for the scientific discovery of root causes, risk and protective factors for mental disorders in global mental health. Systematic research in cultural neuroscience within the research domain criteria (RDoC) framework investigates the fundamental biobehavioral dimensions and observable behavior across cultures. Cultural dimensions are characterized in elements of circuit-based mechanisms and behavior across a range of analysis. Research approaches in cultural neuroscience within the RDoC framework advance the evidence-based resources for the development and implementation of cures, preventions and interventions to mental disorders in global mental health. This review presents a novel synthesis of foundations in cultural neuroscience within the research domain criteria framework to advance integrative, translational efforts in discovery and delivery science of mental disorders across cultural contexts in global mental health.
全面了解大脑的基本分子和细胞机制，对于在全球精神卫生领域科学发现精神障碍的根本原因、风险因素和保护因素至关重要。在研究领域标准（RDoC）框架内进行的文化神经科学系统研究，调查了跨文化的基本生物行为维度和可观察行为。文化维度在一系列分析中的基于回路的机制和行为要素中得以体现。RDoC框架内的文化神经科学研究方法，为全球精神卫生领域精神障碍的治疗、预防和干预的开发与实施，提供了循证资源。本综述提出了研究领域标准框架内文化神经科学基础的新综合，以推动全球精神卫生领域跨文化背景下精神障碍发现与传播科学的整合性、转化性工作。
