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波兰人群中Gc基因(维生素D结合蛋白)的亚型

Subtypes of the Gc gene (vitamin D binding protein) in the Polish population.

作者信息

Leśko D, Schlesinger D, Hałasa J, Mańczak M

机构信息

Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.

出版信息

Arch Immunol Ther Exp (Warsz). 1988;36(6):687-93.

PMID:3254118
Abstract

Gc subtypes were analyzed by isoelectric focusing on thin-layer polyacrylamide gel. In the sample of the Polish population including 278 persons, six Gc phenotypes were encountered: 1S, 1F-1S, 1F, 2-1S, 2-1F, 2 with the following frequencies: 0.342, 0.151, 0.014, 0.360, 0.072 and 0.061. Frequency of Gc1S was 0.597, Gc1F - 0.126 and Gc2 - 0.277. It was shown that a group system of the Gc protein in the Polish population was in good agreement with Hardy Weinberg equilibrium.

摘要

通过在薄层聚丙烯酰胺凝胶上进行等电聚焦分析Gc亚型。在包含278人的波兰人群样本中,发现了六种Gc表型:1S、1F-1S、1F、2-1S、2-1F、2,其频率如下:0.342、0.151、0.014、0.360、0.072和0.061。Gc1S的频率为0.597,Gc1F为0.126,Gc2为0.277。结果表明,波兰人群中Gc蛋白的群体系统与哈迪-温伯格平衡高度一致。

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