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非酒精性脂肪肝与急性脑梗死之间的关联:一项系统评价与荟萃分析方案

Association between non-alcoholic fatty liver and acute cerebral infarction: a protocol of systematic review and meta-analysis.

作者信息

Zhang Ya-Juan, Liu Wen-Juan

机构信息

Department of Neurology, First Affiliated Hospital of Jiamusi University, Jiamusi , China.

出版信息

Medicine (Baltimore). 2020 Jun 12;99(24):e20351. doi: 10.1097/MD.0000000000020351.

Abstract

BACKGROUND

This study will systematically synthesize the evidence on the potential association between non-alcoholic fatty liver (NAFL) and acute cerebral infarction (ACI).

METHODS

We will propose literature search in electronic databases (MEDLINE, EMBASE, Cochrane Library, Scopus, Web of Science, WANGFANG, and China National Knowledge Infrastructure) from the source to March 1, 2020. There are no restrictions related to the language and publication status. Two review authors will separately carry out records selection, data extraction and study quality assessment. Any divisions will be solved by discussion with consulting a third review author. We will use RevMan 5.3 software to perform data analysis.

RESULTS

The present study will afford additional insight into the investigation the association between NAFL and ACI.

CONCLUSION

The results of this study will provide helpful evidence to explore the association between NAFL and ACI.Study registration number: INPLASY202040102.

摘要

背景

本研究将系统地综合关于非酒精性脂肪肝(NAFL)与急性脑梗死(ACI)之间潜在关联的证据。

方法

我们将检索电子数据库(MEDLINE、EMBASE、Cochrane图书馆、Scopus、科学网、万方和中国知网)中从建库至2020年3月1日的文献。对语言和出版状态没有限制。两名综述作者将分别进行文献筛选、数据提取和研究质量评估。任何分歧将通过与第三位综述作者讨论来解决。我们将使用RevMan 5.3软件进行数据分析。

结果

本研究将为NAFL与ACI之间关联的调查提供更多见解。

结论

本研究结果将为探索NAFL与ACI之间的关联提供有用证据。研究注册号:INPLASY202040102。

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引用本文的文献

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Mechanisms of Non-Alcoholic Fatty Liver Disease in the Metabolic Syndrome. A Narrative Review.
Antioxidants (Basel). 2021 Feb 10;10(2):270. doi: 10.3390/antiox10020270.

本文引用的文献

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Clinical observation in edaravone treatment for acute cerebral infarction.
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Efficacy of Danshen Class Injection in the Treatment of Acute Cerebral Infarction: A Bayesian Network Meta-Analysis of Randomized Controlled Trials.
Evid Based Complement Alternat Med. 2019 Feb 3;2019:5814749. doi: 10.1155/2019/5814749. eCollection 2019.
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Efficacy of Minimally Invasive Intervention in Patients With Acute Cerebral Infarction.
J Cardiovasc Pharmacol. 2019 Jan;73(1):22-26. doi: 10.1097/FJC.0000000000000625.
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Associations between nonalcoholic fatty liver disease and ischemic stroke.
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Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
J Stroke Cerebrovasc Dis. 2017 Nov;26(11):2587-2594. doi: 10.1016/j.jstrokecerebrovasdis.2017.06.012. Epub 2017 Jun 29.
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Nonalcoholic fatty liver disease in patients with acute ischemic stroke is associated with more severe stroke and worse outcome.
J Clin Lipidol. 2017 Jul-Aug;11(4):915-919. doi: 10.1016/j.jacl.2017.04.115. Epub 2017 May 10.

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