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急性脑梗死患者血清脂蛋白水平与认知障碍的关联:系统评价与Meta分析方案

Association between serum lipoprotein levels and cognitive impairment in acute cerebral infarction: A protocol for systematic review and meta-analysis.

作者信息

Wei Chun-Jie, Zou Chun-Ying, Wang Zeng-Mian, Jiang Yao-Jia

机构信息

Third Ward of Neurology Department.

Fourth Ward of Neurology Department, First Affiliated Hospital of Jiamusi University, Jiamusi, China.

出版信息

Medicine (Baltimore). 2020 May;99(20):e20178. doi: 10.1097/MD.0000000000020178.

Abstract

BACKGROUND

The objective of this study is to examine the association between serum lipoprotein levels (SLL) and cognitive impairment (CI) in patients with acute cerebral infarction (ACI).

METHODS

All published studies will be searched from the following electronic databases: PubMed, EMBASE, Cochrane Library, PsycINFO, Web of Science, WANGFANG, and China National Knowledge Infrastructure from inauguration of each electronic database up to March 1, 2020. In addition, we will also search other sources, such as dissertations, Google scholar, conference proceedings, and reference lists of relevant reviews. We will not apply any language restrictions to the electronic databases. Two researchers will independently carry out literature selection, data collection, and methodological quality. A third researcher will help to solve any divergences by discussion. The RevMan 5.3 software will be employed to pool the collected data and to analyze the outcome data.

RESULTS

This study will scrutinize the association between SLL and CI in patients with ACI.

CONCLUSIONS

The results of this study will present helpful evidence of the association between SLL and CI in patients with ACI.Registration number: INPLASY202040018.

摘要

背景

本研究旨在探讨急性脑梗死(ACI)患者血清脂蛋白水平(SLL)与认知障碍(CI)之间的关联。

方法

将从以下电子数据库检索所有已发表的研究:PubMed、EMBASE、Cochrane图书馆、PsycINFO、Web of Science、万方数据库和中国知网,检索时间从各电子数据库创建至2020年3月1日。此外,我们还将检索其他来源,如学位论文、谷歌学术、会议论文集以及相关综述的参考文献列表。对电子数据库不设任何语言限制。两名研究人员将独立进行文献筛选、数据收集和方法学质量评估。第三名研究人员将通过讨论帮助解决任何分歧。将使用RevMan 5.3软件汇总收集到的数据并分析结果数据。

结果

本研究将仔细审查ACI患者中SLL与CI之间的关联。

结论

本研究结果将为ACI患者中SLL与CI之间的关联提供有用证据。注册号:INPLASY202040018。

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