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针刺对乳腺癌内分泌治疗副作用的维持效果:一项系统评价与Meta分析方案

The maintenance effect of acupuncture on the side effects of breast cancer endocrine therapy: A protocol for systematic review and meta analysis.

作者信息

Shi Kejin, Tang Ying, He Fengyi, Xiao Xiao, Zhang Jiayuan, Jin Yuxia, Wang Yunxia, Zhang Qi

机构信息

Chengdu university of traditional Chinese medicine, Chengdu, Sichuan province, China.

出版信息

Medicine (Baltimore). 2020 Jun 12;99(24):e20567. doi: 10.1097/MD.0000000000020567.


DOI:10.1097/MD.0000000000020567
PMID:32541483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7302662/
Abstract

BACKGROUND: Breast cancer is common among women throughout the world and endocrine therapy is an established part of its treatment. But, unfortunately, this has also resulted in intolerable side effects affecting the quality of life. Acupuncture has been widely used to treat endocrine-related side effects in patients with breast cancer, but how long its effect can be maintained has not been published. The systematic review is designed to evaluate the maintenance efficacy of acupuncture for related side effects after breast cancer endocrine therapy. METHODS AND ANALYSIS: We will search for the following databases: PubMed, Embase, Cochrane Library, Web of Science, including China National Knowledge Infrastructure (CNKI), WanFang Data, Technology Periodical Database (VIP), and China Biology Medicine (CBM) from inception to May 2020. Two reviewers will search these databases, collect all articles, and assess the quality of studies separately, and there will be no limitations on language. The primary outcomes will be assessed using acupuncture for endocrine-related hot flashes and joint pain duration (1 month, 3 months, 6 months). Measurement tools include the Kupperman index, Brief Pain Inventory Short Form (BPI-SF), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Brief Pain Inventory-Short (BPI-SF). We will use RevMan V.5.3 for meta-analysis and employ the Grading of Recommendations Assessment, Development and Evaluation System to assess the quality of evidence. RESULTS: This systematic review will evaluate the maintenance efficacy of acupuncture on the side effects of breast cancer endocrine therapy. CONCLUSION: This study will provide high-quality current evidence of how long its effect can be maintained after acupuncture for related side effects after breast cancer endocrine therapy. ETHICS AND DISSEMINATION: Ethical committee approval is not required for this systematic review as patient data will not be collected. This study will help to inform doctors and researchers on the duration of acupuncture treatment for endocrine-related hot flashes and joint pain. The results will be published in a peer-reviewed journal and will be disseminated in relevant conferences. INPLASY REGISTRATION NUMBER: INPLASY202040024.

摘要

背景:乳腺癌在全球女性中很常见,内分泌治疗是其治疗的既定组成部分。但不幸的是,这也导致了影响生活质量的难以忍受的副作用。针灸已被广泛用于治疗乳腺癌患者的内分泌相关副作用,但其效果能维持多久尚未见报道。本系统评价旨在评估针灸对乳腺癌内分泌治疗后相关副作用的维持疗效。 方法与分析:我们将检索以下数据库:从建库至2020年5月的PubMed、Embase、Cochrane图书馆、Web of Science,包括中国知网(CNKI)、万方数据、维普期刊数据库(VIP)和中国生物医学文献数据库(CBM)。两名评价员将检索这些数据库,收集所有文章,并分别评估研究质量,且对语言无限制。主要结局将通过针灸治疗内分泌相关潮热和关节疼痛的持续时间(1个月、3个月、6个月)进行评估。测量工具包括库珀曼指数、简明疼痛问卷简表(BPI-SF)、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、简明疼痛问卷-简短版(BPI-SF)。我们将使用RevMan V.5.3进行荟萃分析,并采用推荐分级评估、制定和评价系统来评估证据质量。 结果:本系统评价将评估针灸对乳腺癌内分泌治疗副作用的维持疗效。 结论:本研究将提供高质量的当前证据,证明针灸治疗乳腺癌内分泌治疗相关副作用后其效果能维持多久。 伦理与传播:本系统评价无需伦理委员会批准,因为不会收集患者数据。本研究将有助于告知医生和研究人员针灸治疗内分泌相关潮热和关节疼痛的持续时间。研究结果将发表在同行评审期刊上,并在相关会议上传播。 INPLASY注册号:INPLASY202040024。

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