住院期间药物负担指数（DBI）变化较大，住院跌倒患者 30 天再入院率增加。

Greater Changes in Drug Burden Index (DBI) during Hospitalization and Increased 30-Day Readmission Rates among Older In-Hospital Fallers.

机构信息

aDepartment of Pharmacotherapy, System College of Pharmacy, University of North Texas Health Sciences Center, Fort Worth, TX, USA.

bDivision of Geriatric and Palliative Medicin, Department of Internal Medicine, UTHealth McGovern Medical School, Houston, TX, USA.

出版信息

Hosp Top. 2020 Apr-Jun;98(2):59-67. doi: 10.1080/00185868.2020.1777916. Epub 2020 Jun 16.

DOI:10.1080/00185868.2020.1777916

PMID:32543345

Abstract

A higher drug burden index (DBI) is known to be associated with pre-admission falls leading to hospitalization. We investigated whether a mean difference in DBI (ΔDBI) between the events of in-hospital falls and hospital admission was associated with 30-day readmission in 113 patients ≥50 years who fell during their hospital stays between 2007 and 2014. A greater ΔDBI (≥0.09) was positively associated with higher 30-day readmission rates (incident rate ratio: 2.02; 95% confidence interval: 1.49-2.74). An effort to keep DBI low may thus decrease 30-day readmissions for older in-hospital fallers.

摘要

已知较高的药物负担指数（DBI）与导致住院的入院前跌倒有关。我们研究了在 2007 年至 2014 年住院期间跌倒的 113 名≥50 岁的患者中，住院期间跌倒事件与入院之间的 DBI 平均值差异（ΔDBI）是否与 30 天再入院相关。较大的 ΔDBI（≥0.09）与更高的 30 天再入院率呈正相关（发生率比：2.02；95%置信区间：1.49-2.74）。因此，努力降低 DBI 可能会降低老年住院跌倒者的 30 天再入院率。