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构建并分析三角双锥和五角双锥的双链结构。

Construction and Analysis of Double Helix for Triangular Bipyramid and Pentangular Bipyramid.

机构信息

Key Laboratory of China's Ethnic Languages and Information Technology of Ministry of Education, Northwest Minzu University, Lanzhou 730030, China.

Key Laboratory of Streaming Data Computing Technologies and Application, Northwest Minzu University, Lanzhou 730030, China.

出版信息

Comput Math Methods Med. 2020 May 14;2020:5609593. doi: 10.1155/2020/5609593. eCollection 2020.

DOI:10.1155/2020/5609593
PMID:32549907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7255045/
Abstract

DNA cages can be joined together to make larger 3D nanostructures on which molecular electronic circuits and tiny containers are built for drug delivery. The mathematical models for these promising nanomaterials play important roles in clarifying their assembly mechanism and understanding their structures. In this study, we propose a mathematical and computer method to construct permissible topological structures with double-helical edges for a triangular bipyramid and pentangular bipyramid. Furthermore, we remove the same topological links, without eliminating the nonrepeated ones for a triangular bipyramid and pentangular bipyramid. By analyzing characteristics of these unique links, some self-assembly and statistic rules are discussed. This study may obtain some new insights into the DNA assembly from the viewpoint of mathematics, promoting the comprehending and design efficiency of DNA polyhedra with required topological structures.

摘要

DNA 笼可以连接在一起，形成更大的 3D 纳米结构，在这些结构上构建分子电子电路和微小容器，用于药物输送。这些有前途的纳米材料的数学模型在阐明其组装机制和理解其结构方面发挥着重要作用。在这项研究中，我们提出了一种数学和计算机方法，用于构建具有双螺旋边缘的允许的拓扑结构，用于三角双锥和五角双锥。此外，我们去除了三角双锥和五角双锥的相同拓扑链接，而不消除非重复的链接。通过分析这些独特链接的特征，讨论了一些自组装和统计规则。这项研究可能会从数学的角度获得一些关于 DNA 组装的新见解，从而提高具有所需拓扑结构的 DNA 多面体的理解和设计效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/635ebe1112c6/CMMM2020-5609593.008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/a8333a744d15/CMMM2020-5609593.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/635ebe1112c6/CMMM2020-5609593.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/81f63ef68ad7/CMMM2020-5609593.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/a6755580768c/CMMM2020-5609593.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/b048c0116a45/CMMM2020-5609593.003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/ed751b9e419e/CMMM2020-5609593.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/67d81aa42591/CMMM2020-5609593.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/a8333a744d15/CMMM2020-5609593.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b29/7255045/635ebe1112c6/CMMM2020-5609593.008.jpg

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本文引用的文献

1
The calculation of topological structures of strands-based DNA trigonal bipyramids.基于链的 DNA 三角双锥的拓扑结构计算。
J Mol Graph Model. 2020 Mar;95:107492. doi: 10.1016/j.jmgm.2019.107492. Epub 2019 Nov 20.
2
Configuration of DNA polyhedra of truncated tetrahedron, cuboctahedron, truncated octahedron.截断四面体、截角八面体、截断八面体的 DNA 多面体的结构。
J Theor Biol. 2019 Jul 7;472:4-10. doi: 10.1016/j.jtbi.2019.03.020. Epub 2019 Mar 27.
3
One-time-pad cryptography scheme based on a three-dimensional DNA self-assembly pyramid structure.
基于三维 DNA 自组装金字塔结构的一次性密码本加密方案。
PLoS One. 2018 Nov 6;13(11):e0206612. doi: 10.1371/journal.pone.0206612. eCollection 2018.
4
DNA Octahedron-Based Fluorescence Nanoprobe for Dual Tumor-Related mRNAs Detection and Imaging.基于 DNA 八面体的荧光纳米探针用于双重肿瘤相关 mRNA 的检测和成像。
Anal Chem. 2018 Oct 16;90(20):12059-12066. doi: 10.1021/acs.analchem.8b02847. Epub 2018 Oct 2.
5
A Telomerase-Responsive DNA Icosahedron for Precise Delivery of Platinum Nanodrugs to Cisplatin-Resistant Cancer.一种端粒酶响应的 DNA 二十面体，用于精确递送至顺铂耐药癌症的铂纳米药物。
Angew Chem Int Ed Engl. 2018 May 4;57(19):5389-5393. doi: 10.1002/anie.201801195. Epub 2018 Apr 14.
6
DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery.用于生物应用的 DNA 四面体纳米结构：生物传感器和药物传递。
Analyst. 2017 Sep 8;142(18):3322-3332. doi: 10.1039/c7an01154g.
7
Intrinsic Dynamics Analysis of a DNA Octahedron by Elastic Network Model.基于弹性网络模型的DNA八面体的本征动力学分析
Molecules. 2017 Jan 16;22(1):145. doi: 10.3390/molecules22010145.
8
Computer-Aided Production of Scaffolded DNA Nanostructures from Flat Sheet Meshes.计算机辅助从平面网格中生成支架 DNA 纳米结构。
Angew Chem Int Ed Engl. 2016 Jul 25;55(31):8869-72. doi: 10.1002/anie.201602446. Epub 2016 Jun 15.
9
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Bioconjug Chem. 2016 Apr 20;27(4):905-10. doi: 10.1021/acs.bioconjchem.5b00680. Epub 2016 Mar 17.
10
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