Berthé-Sanou Lalla, Sanou Maïmouna, Berthé Abdramane, Ouédraogo Rayende, Sawadogo Adrien B, Drabo Joseph, Moh Raoul, Tubiana Roland, Slama Laurence, Desclaux Alice
Sante Publique. 2019 September-October;31(6):855-864. doi: 10.3917/spub.196.0855.
Adherence to antiretroviral therapy is a major obstacle to achieving WHO target 3. In West Africa, however, there is a lack of evidence on the most feasible, acceptable and effective adherence reinforcement measures and users' perceptions of these measures. The purpose of this article is to analyze the perceptions of PLHIV (people living with HIV) on ART reinforcement measures in Burkina Faso.
In Ouagadougou and Bobo-Dioulasso care centers, THILAO Research Project (ANRS 12269) enrolled PLHIV experiencing therapeutic failure on 2nd line antiretroviral treatment, and offered to them adherence reinforcement measures. We conducted a qualitative socio-anthropological study to explore their perceptions. Data were collected through repeated individual interviews with 37 PLHIV.
The 31 participants who completed interviews were relatively satisfied with the measures to support adherence. Three measures (pill organizer, weekly phone calls by a member of the team, cellphone alarm reminders) were perceived as simple, effective, discreet, adapted to both illiterate and educated people. Three other measures (home visits, involvement of a member of the family and SMS) were not highly appreciated as they expose to the disclosure of HIV+ status and /or stigmatization. Two measures (support group, frequent visits to the care center) were less selected because considered tedious.
PLHIV chosed and used the most appropriate adherence measures for their profile / context. The most feasible and acceptable measures identified could be offered to PLHIV at risk of non-compliance in West African ART programs.
坚持抗逆转录病毒治疗是实现世界卫生组织目标3的主要障碍。然而，在西非，缺乏关于最可行、可接受和有效的依从性强化措施以及使用者对这些措施看法的证据。本文旨在分析布基纳法索艾滋病毒感染者（PLHIV）对艾滋病治疗强化措施的看法。
在瓦加杜古和博博迪乌拉索的护理中心，提拉奥研究项目（ANRS 12269）招募了在二线抗逆转录病毒治疗中出现治疗失败的艾滋病毒感染者，并为他们提供依从性强化措施。我们进行了一项定性社会人类学研究，以探索他们的看法。通过对37名艾滋病毒感染者进行反复的个人访谈收集数据。
完成访谈的31名参与者对支持依从性的措施相对满意。三种措施（药盒、团队成员每周电话随访、手机闹钟提醒）被认为简单、有效、不张扬，适合文盲和受过教育的人。另外三种措施（家访、家庭成员参与和短信）不太受欢迎，因为它们可能导致艾滋病毒阳性状态的暴露和/或污名化。两种措施（支持小组、频繁前往护理中心）较少被选择，因为被认为很繁琐。
艾滋病毒感染者根据自身情况/背景选择并使用了最合适的依从性措施。所确定的最可行和可接受的措施可提供给西非艾滋病治疗项目中存在不依从风险的艾滋病毒感染者。
