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氟-18 标记的 Fluciclovine PET/CT 在原发性和生化复发前列腺癌管理中的应用。

Fluorine-18-Labeled Fluciclovine PET/CT in Primary and Biochemical Recurrent Prostate Cancer Management.

机构信息

Department of Radiology, West Virginia University Health Sciences Center, 1 Medical Center Dr, Morgantown, WV 26505.

Department of Radiology, UT Southwestern Medical Center, Dallas, TX.

出版信息

AJR Am J Roentgenol. 2020 Aug;215(2):267-276. doi: 10.2214/AJR.19.22404. Epub 2020 Jun 17.

Abstract

The purpose of this article is to review the utility of F-fluciclovine PET/CT in the evaluation of recurrent prostate cancer. Fluorine-18-labeled fluciclovine PET/CT has shown promise in the evaluation of recurrent prostate cancer. Its performance has been superior to that of other imaging modalities. It has had good diagnostic accuracy, especially in the detection of extra-prostatic disease recurrence, and the findings have an impact on treatment planning. Gallium-68-labeled prostate-specific membrane antigen PET/CT has also had excellent performance in the detection of biochemically recurrent prostate cancer with detection rates superior to those of fluciclovine PET/CT.

摘要

本文旨在回顾 F-氟代盐酸仑伐替尼 PET/CT 在复发性前列腺癌评估中的应用。氟[18F]氟代盐酸仑伐替尼 PET/CT 在复发性前列腺癌的评估中显示出了一定的前景。其性能优于其他成像方式。它具有良好的诊断准确性,特别是在检测前列腺外疾病复发方面,其结果对治疗计划有影响。镓[68Ga]标记的前列腺特异性膜抗原 PET/CT 在检测生化复发的前列腺癌方面也具有优异的性能,其检测率优于氟代盐酸仑伐替尼 PET/CT。

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