Laboratory Centre, Hanoi University of Public Health, Hanoi, Vietnam.
Department of Viral Infection and International Health, Graduate School of Medical Science, Kanazawa University, Japan.
Am J Mens Health. 2020 May-Jun;14(3):1557988320926743. doi: 10.1177/1557988320926743.
To investigate the distribution of opportunistic infections (OIs) and factors associated with acquiring OIs in human immunodeficiency virus (HIV)-infected men who have sex with men (MSM) in comparison to those of heterosexual patients.
A cross-sectional study was conducted on 82 HIV-infected MSM and 120 HIV-infected heterosexual men in Bach Mai Hospital, Hanoi, Vietnam. Demographical characteristics and clinical data were collected and analyzed using appropriate statistics (Mann-Whitney, Chi-square, Fisher's exact test, and logistic regression).
The prevalence of OIs among MSM and heterosexual patients were 63.4% and 81.7%, respectively. The most frequent OI in the MSM group was human papilloma virus (HPV) (11%), followed by hepatitis B virus (8.5%), mycobacterium tuberculosis (7.3%), and Talaromycosis (2.4%).
Multivariate logistic regression analysis showed that buying sex (odds ratio (OR) = 4, 95% confidence interval (CI): 1.13-14.25) and injecting drugs (OR = 13.05, 95% CI: 2.39-71.21) were associated with increased odds of having OIs in heterosexual patients while increasing age (OR = 1.1, 95% CI: 1.01-1.24) was correlated to increased odd of acquiring OIs in the MSM group. HIV-infected MSM accumulates OIs with increasing age, while heterosexual individuals increase opportunistic infections by buying sex or injecting drugs.
与异性恋患者相比，调查感染艾滋病毒（HIV）的男男性行为（MSM）者中机会性感染（OI）的分布情况及获得 OI 的相关因素。
在越南河内的白梅医院对 82 名 HIV 感染的 MSM 和 120 名 HIV 感染的异性恋男性进行了一项横断面研究。收集和分析人口统计学特征和临床数据，并使用适当的统计方法（Mann-Whitney、卡方、Fisher 确切检验和逻辑回归）进行分析。
MSM 和异性恋患者中 OI 的患病率分别为 63.4%和 81.7%。MSM 组中最常见的 OI 是人乳头瘤病毒（HPV）（11%），其次是乙型肝炎病毒（8.5%）、结核分枝杆菌（7.3%）和塔勒氏霉病（2.4%）。
多变量逻辑回归分析显示，异性恋患者中，性交易（优势比（OR）=4，95%置信区间（CI）：1.13-14.25）和注射毒品（OR=13.05，95%CI：2.39-71.21）与 OI 的发生几率增加有关，而年龄增加（OR=1.1，95%CI：1.01-1.24）与 MSM 组 OI 发生几率增加有关。HIV 感染的 MSM 随着年龄的增长而积累 OI，而异性恋个体则通过性交易或注射毒品增加机会性感染。
