Pittsburgh Mining Research Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Pittsburgh, PA, USA.
Institute of Analytical and Bioanalytical Chemistry, Ulm University, Ulm, Germany.
Arch Environ Occup Health. 2021;76(3):134-144. doi: 10.1080/19338244.2020.1779018. Epub 2020 Jun 18.
Respirable dust can pass beyond ciliated airways of the respiratory tract and influence adverse health effects. Health effects can be studied using samples generated from bulk dust segregation. Because previous segregation methods diverge from size-selection criteria of the international convention for respirable particles (ICRP), a method was developed to approximate the ICRP. The method was compared to an ideal sampler by measuring the sample collection bias. The comparison shows that the uncertainty due to the bias was 0.10 based on European Standard EN13205:2014 criteria, which indicates that the segregator effectively follows the ICRP. Respirable particle size distributions were confirmed by an aerodynamic particle sizer and by computer-controlled scanning electron microscopy. Consequently, a systematic way to generate respirable powders for health effects studies and chemical analyses was developed.
可吸入粉尘可以穿透呼吸道的纤毛气道，并影响不良健康影响。可以使用从散装粉尘分离产生的样品来研究健康影响。由于以前的分离方法与国际可吸入颗粒物公约（ICRP）的粒径选择标准不同，因此开发了一种方法来近似 ICRP。通过测量样品收集偏差，将该方法与理想采样器进行了比较。比较表明，根据欧洲标准 EN13205：2014 标准，由于偏差引起的不确定性为 0.10，这表明分离器有效地遵循了 ICRP。通过空气动力学颗粒尺寸分析仪和计算机控制的扫描电子显微镜确认了可吸入颗粒物的粒径分布。因此，开发了一种用于健康影响研究和化学分析的生成可吸入粉尘的系统方法。
