Pediatric Developmental Disorders Research Center, Hamadan University of Medical Sciences , Hamadan, Iran.
Autism Spectrum disorders Research Center, Hamadan University of Medical Sciences , Hamadan, Iran.
Women Health. 2020 Sep;60(8):939-945. doi: 10.1080/03630242.2020.1779905. Epub 2020 Jun 18.
There is high prevalence of both migraine and endometriosis; however, the association between both is controversial. This systematic review evaluated the association between endometriosis and the risk of migraine headache. A search was done of the following international electronic bibliographic databases including: PubMed, Web of Science, and Scopus to May 2020. Heterogeneity among studies was determined by Q-test and I statistic. Publication bias was assessed by Begg's and Egger's tests. The results were reported using the odds ratio (OR) estimate with its 95% confidence interval (CI) using a random-effects model. The search identified 802 articles with 287,174 participants. There was a significant association between endometriosis and the risk of migraine headache (OR = 1.56; 95% CI: 1.21, 1.90). Based on the Newcastle Ottawa Statement Manual (NOS) scale, all studies had high quality. The findings showed that endometriosis was significantly associated with an increased risk of migraine headache. Future research should be focused on measures that could help to reduce the risk of migraine headache among women with endometriosis.
偏头痛和子宫内膜异位症的患病率都很高；然而，两者之间的关联仍存在争议。本系统评价评估了子宫内膜异位症与偏头痛风险之间的关联。检索了以下国际电子书目数据库：PubMed、Web of Science 和 Scopus，检索时间截至 2020 年 5 月。通过 Q 检验和 I 统计量确定研究间的异质性。通过 Begg 和 Egger 检验评估发表偏倚。使用随机效应模型，报告结果时使用比值比（OR）估计值及其 95%置信区间（CI）。搜索共确定了 802 篇文章，涉及 287174 名参与者。子宫内膜异位症与偏头痛风险之间存在显著关联（OR=1.56；95%CI：1.21，1.90）。根据 Newcastle Ottawa 声明手册（NOS）量表，所有研究的质量都很高。研究结果表明，子宫内膜异位症与偏头痛风险增加显著相关。未来的研究应集中于可能有助于降低子宫内膜异位症女性偏头痛风险的措施。
