Pereira Filho R A, Sevá-Pereira A, de Magalhães A F
Departamento de Clínica Médica, Faculdade de Ciências Médicas da Universidade Estadual de Campinas (UNICAMP).
Arq Gastroenterol. 1988 Apr-Jun;25(2):75-81.
Absorption of medium chain triglycerides (MCT) was estimated in 10 patients with stagnant loop syndrome (SLS). Six patients had steatorrhea due to gastrojejunal anastomosis and 4 due to diabetic neuropathy. The diagnosis of SLS was confirmed by antibiotic therapeutic test after exclusion of other causes of malabsorption syndrome. Each patient was submitted to 2 types of diet during one week each, differing only in the type of added lipid. In the diet with long chain triglycerides (LCT), soy oil and butter were added. In the diet, with medium chain triglycerides, only MCT oil from babaçu was added. The excretion of lipid was determined in the feces in the last 3 days of each diet. The results showed that the medium fecal lipid excretion was 48.6 (sd = 19.8) g/d in the LCT diet and 26.6 (sd = 13.8) g/d in the MCT [d = 22.0; s(d) = 3.10; t = 7.10; p less than 0.001], which indicates that in patients with SLS, MCT diet was better absorbed than LCT diet. It is suggested that MCT oil may be used as a caloric source during nutritional recovery in SLS.
对10例肠淤滞综合征（SLS）患者的中链甘油三酯（MCT）吸收情况进行了评估。6例患者因胃空肠吻合术出现脂肪泻，4例因糖尿病性神经病变出现脂肪泻。在排除吸收不良综合征的其他病因后，通过抗生素治疗试验确诊为SLS。每位患者在一周内分别接受两种饮食，仅添加的脂质类型不同。在含长链甘油三酯（LCT）的饮食中，添加了大豆油和黄油。在含中链甘油三酯的饮食中，仅添加了巴巴苏的MCT油。在每种饮食的最后3天测定粪便中的脂质排泄量。结果显示，LCT饮食中粪便脂质排泄量中位数为48.6（标准差=19.8）g/天，MCT饮食中为26.6（标准差=13.8）g/天[差值=22.0；标准误（s(d)）=3.10；t=7.10；P<0.001]，这表明在SLS患者中，MCT饮食的吸收优于LCT饮食。建议在SLS患者营养恢复期间，MCT油可作为热量来源。
