Department of Ophthalmology, McGill University, Montreal, QC, Canada.
LASIK MD, 1250 Rene-Levesque Blvd W, MD Level, Montreal, QC, H3B 4W8, Canada.
BMC Ophthalmol. 2020 Jun 17;20(1):234. doi: 10.1186/s12886-020-01481-2.
To evaluate laser-assisted in situ keratomileusis (LASIK) outcomes, subjective quality of vision (QoV) and patient satisfaction in eyes with very high myopia (VHM) above - 10.00 diopters (D).
Consecutive myopic and myopic-astigmatism eyes with spherical equivalent (SEQ) ranging between - 10.00 to - 13.50 D underwent LASIK with the WaveLight® Allegretto Wave® Eye-Q 400 Hz excimer laser. Treatment accuracy, efficacy, safety, stability, cylinder vectors, and higher-order aberrations were evaluated, together with subjective QoV and night vision disturbances (NVDs).
114 eyes had a preoperative SEQ of - 11.02 ± 0.81 D, with a median follow-up of 24 months. A total of 72, 84, and 94% of eyes were within ± 0.50, ± 0.75 and ± 1.00 D of intended SEQ (R = 0.71). The efficacy index was 0.93 ± 0.20, with 51 and 81% of eyes achieving 20/20 and 20/25. The astigmatism correction index was 0.95 ± 0.33. The safety index was 1.05 ± 0.12. The average myopic regression was - 0.51 ± 0.38 D. Preoperative QoV scores improved significantly postoperatively (7.5 ± 0.8 vs. 9.1 ± 0.7; P < 0.001), with less NVDs (P < 0.001). Total, spherical and coma root mean square (RMS) postoperative ocular higher-order aberrations were 1.07 ± 0.34, 0.67 ± 0.25, and 0.70 ± 0.40 μm.
Very high myopia LASIK between - 10.00 to - 13.50 D is safe and results in good visual outcomes, with high patient satisfaction and a significant improvement in patient-reported QoV after surgery. Appropriately selected patients within this very high myopia group can be included as LASIK candidates.
评估激光辅助原位角膜磨镶术（LASIK）在 10.00 屈光度以上的超高近视（VHM）眼中的疗效，以及视觉质量（QoV）和患者满意度。
对等效球镜（SEQ）范围在-10.00 至-13.50 D 的近视和近视散光眼进行 LASIK 手术，使用 WaveLight® Allegretto Wave® Eye-Q 400 Hz 准分子激光。评估治疗准确性、疗效、安全性、稳定性、圆柱矢量和高阶像差，以及主观 QoV 和夜视障碍（NVDs）。
114 只眼术前 SEQ 为-11.02±0.81 D，中位随访时间为 24 个月。共有 72%、84%和 94%的眼在±0.50、±0.75 和±1.00 D 的目标 SEQ 范围内（R=0.71）。功效指数为 0.93±0.20，51%和 81%的眼达到 20/20 和 20/25。散光矫正指数为 0.95±0.33。安全性指数为 1.05±0.12。平均近视回退为-0.51±0.38 D。术前 QoV 评分术后显著提高（7.5±0.8 与 9.1±0.7；P<0.001），夜视障碍减少（P<0.001）。术后总、球镜和彗差均方根（RMS）眼高阶像差分别为 1.07±0.34、0.67±0.25 和 0.70±0.40μm。
-10.00 至-13.50 D 的超高近视 LASIK 是安全的，可获得良好的视觉效果，患者满意度高，术后患者报告的 QoV 显著改善。在该超高近视组中选择合适的患者可以作为 LASIK 候选者。
