Paul Jayanta
Department of Gastroenterology, Desun Hospital and Heart Institute, Kolkata, India.
Prague Med Rep. 2020;121(2):118-123. doi: 10.14712/23362936.2020.11.
Acute on chronic liver failure (ACLF) can be precipitated by several factors such as bacterial infection, alcohol intake, viral hepatitis, surgery, etc. Identification of precipitating factor is an important part of management of ACLF. A middle aged gentleman was presented with features of acute liver failure and after through history and investigations, he was diagnosed as acute on chronic liver failure. Chronic liver disease was first diagnosed after this event of acute insult. Precipitating factor of ACLF was dengue fever in this case report. Therefore, in endemic area of dengue infection, dengue serology tests which are not routinely done should be advised to identify dengue infection as an acute insult in ACLF.
慢加急性肝衰竭（ACLF）可由多种因素诱发，如细菌感染、饮酒、病毒性肝炎、手术等。识别诱发因素是ACLF管理的重要组成部分。一名中年男性表现出急性肝衰竭的特征，经过详细的病史询问和检查后，他被诊断为慢加急性肝衰竭。此次急性损伤事件后首次诊断出慢性肝病。在本病例报告中，ACLF的诱发因素是登革热。因此，在登革热感染流行地区，对于ACLF患者，应建议进行通常不常规开展的登革热血清学检测，以识别登革热感染这一急性损伤因素。
