WHO Country Office for India, New Delhi, India.
Amrita Institute of Medical Sciences, Amrita University, India.
Indian J Tuberc. 2020 Apr;67(2):202-207. doi: 10.1016/j.ijtb.2020.02.001. Epub 2020 Feb 17.
Kerala, the southern Indian state piloted Lung Health Care Project (LHCP) which is a locally adopted version of WHO recommended Practical Approach to Lung health (PAL). The current study assessed the impact of the project on the prescribing practices of doctors and consumption of antibiotics and other drugs.
This study compared performance of primary health care institutions with regard to drug prescriptions and consumptions before and after the implementation of the project. Chronic respiratory disease (CRD) patients in institutions implemented the project were interviewed in the OPD at exit and their prescriptions were documented at baseline and after six months. Focus group discussions were conducted with doctors to explore the reasons behind changes in drug consumption pattern.
In the project implementing institutions, mean number of drugs prescribed for CRDs was 3.88 (SD 1.50) and 2.73 (SD 1.18) at baseline and after six months respectively (p < 0.001). Adjusted odds ratio for prescribing an antibiotic and injection to a CRD patient during impact assessment at institutions implementing project was 0.34 (95% CI 0.15-0.75 p 0.008) and 0.39 (95% CI 0.20-0.74 p 0.004) respectively, as compared to baseline. The factors which helped in reducing antibiotic and injection use as felt by the doctors were presence of a protocol, good quality trainings, supportive supervision and monitoring, availability of alternate drugs and good participation of staff nurses especially in-patient education.
Strict adherence to diagnostic and management algorithms of Lung health care project in a primary health care setting in India helped in reducing pill burden to patients and prescription of antibiotics and injections.
印度南部的喀拉拉邦试行过肺保健项目(LHCP),这是世界卫生组织推荐的实用肺部健康方法(PAL)的本地化版本。本研究评估了该项目对医生处方习惯以及抗生素和其他药物使用的影响。
本研究比较了项目实施前后基层医疗机构的药物处方和使用情况。在项目实施机构中,对门诊的慢性呼吸道疾病(CRD)患者进行访谈,并在基线和 6 个月后记录其处方。还与医生进行了焦点小组讨论,以探讨药物消费模式变化背后的原因。
在项目实施机构中,CRD 患者的处方药物数量从基线时的 3.88(SD 1.50)降至 6 个月后的 2.73(SD 1.18)(p<0.001)。在项目实施机构中,对 CRD 患者进行影响评估时,开抗生素和注射剂的调整后比值比分别为 0.34(95%CI 0.15-0.75,p<0.008)和 0.39(95%CI 0.20-0.74,p<0.004),与基线相比。医生认为有助于减少抗生素和注射剂使用的因素包括存在协议、高质量培训、支持性监督和监测、替代药物的可用性以及工作人员护士(特别是住院患者教育)的良好参与。
在印度基层医疗环境中严格遵守肺保健项目的诊断和管理算法有助于减轻患者的药物负担,并减少抗生素和注射剂的处方。