UDST 的影响：迈向终结结核病的一步。
Impact of UDST: A step forward to end TB.
机构信息
Jhalawar Hospital and Medical College, Jhalawar, Rajasthan, India.
Jhalawar Hospital and Medical College, Jhalawar, Rajasthan, India.
出版信息
Indian J Tuberc. 2020 Apr;67(2):213-215. doi: 10.1016/j.ijtb.2020.02.009. Epub 2020 Mar 3.
BACKGROUND
India is determined to eliminate TB by 2025 despite being a high burden country. Revised National Tuberculosis Control Programme (RNTCP) is being strengthened with introduction of Universal Drug Susceptibility Testing (UDST) for Rifampicin to achieve the elimination status.
METHODOLOGY
We used a before-after comparison of baseline and intervention periods (12 months each) and analyzed data viz CBNAAT performed and case detection for both drug sensitive and drug resistant TB cases.
RESULTS
After implementation of Universal DST, CBNAAT performed raised from 1252 to 3137 (increased by 2.5 times); Rif sensitive cases detected raised from 458 to 1241 (increased by 2.7 times) and Rif resistant cases detected raised from 54 to 82 (increased by 1.5 times) during baseline period (2017) and intervention period (2018).
CONCLUSION
We conclude that introduction of UDST for Rifampicin in RNTCP has given a significant impact with increased case detection in our study.
背景
尽管印度是结核病高负担国家，但仍决心在 2025 年前消灭结核病。修订后的国家结核病控制规划（RNTCP）正在得到加强，引入了利福平普遍药物敏感性检测（UDST），以实现消除状态。
方法
我们使用了基线期和干预期（各 12 个月）的前后比较，并分析了 CBNAAT 检测和敏感及耐药结核病病例检出的数据。
结果
实施普遍药物敏感性检测后，CBNAAT 检测从 1252 例增加到 3137 例（增加了 2.5 倍）；利福平敏感病例从 458 例增加到 1241 例（增加了 2.7 倍），利福平耐药病例从 54 例增加到 82 例（增加了 1.5 倍），分别在基线期（2017 年）和干预期（2018 年）。
结论
我们得出结论，在 RNTCP 中引入利福平普遍药物敏感性检测对我们的研究中病例检出率的提高产生了重大影响。
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