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三种不同后路减压技术治疗腰椎管狭窄症后硬脊膜囊面积的可比增加:NORDSTEN 研究中随机对照试验的放射学结果。

Comparable increases in dural sac area after three different posterior decompression techniques for lumbar spinal stenosis: radiological results from a randomized controlled trial in the NORDSTEN study.

机构信息

Department of Orthopedic Surgery, Ålesund Hospital, Møre and Romsdal Hospital Trust, Ålesund, Norway.

Kysthospitalet in Hagevik. Orthopedic Clinic, Haukeland University Hospital, Bergen, Norway.

出版信息

Eur Spine J. 2020 Sep;29(9):2254-2261. doi: 10.1007/s00586-020-06499-0. Epub 2020 Jun 18.

Abstract

PURPOSE

To investigate changes in dural sac area after three different posterior decompression techniques in patients undergoing surgery for lumbar spinal stenosis. Decompression of the nerve roots is the main surgical treatment for lumbar spinal stenosis. The aim of this study was to radiologically investigate three commonly used posterior decompression techniques.

METHODS

The present study reports data from one of two multicenter randomized trials included in the NORDSTEN study. In the present trial, involving 437 patients undergoing surgery, we report radiological results after three different midline retaining posterior decompression techniques: unilateral laminotomy with crossover (UL) (n = 146), bilateral laminotomy (BL) (n = 142) and spinous process osteotomy (SPO) (n = 149). MRI was performed before and three months after surgery. The increase in dural sac area and Schizas grade at the most stenotic level was evaluated. Three different predefined surgical indicators of substantial decompression were used: (1) postoperative dural sac area of > 100 mm, (2) increase in the dural sac area of at least 50% and (3) postoperative Schizas grade A or B.

RESULTS

No differences between the three surgical groups were found in the mean increase in dural sac area. Mean values were 66.0 (SD 41.5) mm in the UL-group, 71.9 (SD 37.1) mm in the BL-group and 68.1 (SD 41.0) mm in the SPO-group (p = 0.49). No differences in the three predefined surgical outcomes between the three groups were found.

CONCLUSION

For patients with lumbar spinal stenosis, the three different surgical techniques provided the same increase in dural sac area.

CLINICAL TRIAL REGISTRATION

The study is registered at ClinicalTrials.gov reference on November 22th 2013 under the identifier NCT02007083.

摘要

目的

研究三种不同后路减压技术对腰椎管狭窄症患者术后硬脊膜囊面积变化的影响。神经根减压是腰椎管狭窄症的主要手术治疗方法。本研究旨在对三种常用后路减压技术进行影像学研究。

方法

本研究报告了 NORDSTEN 研究中两项多中心随机试验之一的数据。在本试验中,对 437 名接受手术的患者进行了研究,我们报告了三种不同中线保留后路减压技术的影像学结果:单侧椎板切除术加交叉(UL)(n=146)、双侧椎板切除术(BL)(n=142)和棘突截骨术(SPO)(n=149)。术前和术后三个月进行 MRI 检查。评估最狭窄水平的硬脊膜囊面积增加和 Schizas 分级。使用三种不同的预定手术减压指标:(1)术后硬脊膜囊面积>100mm;(2)硬脊膜囊面积增加至少 50%;(3)术后 Schizas 分级 A 或 B。

结果

三组手术患者的硬脊膜囊面积平均增加无差异。UL 组平均增加 66.0(SD 41.5)mm,BL 组增加 71.9(SD 37.1)mm,SPO 组增加 68.1(SD 41.0)mm(p=0.49)。三组患者的三种预定手术结果均无差异。

结论

对于腰椎管狭窄症患者,三种不同的手术技术均能使硬脊膜囊面积增加。

临床试验注册

该研究于 2013 年 11 月 22 日在 ClinicalTrials.gov 注册,注册号为 NCT02007083。

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