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生活在石油和天然气加工区的环境性身材矮小儿童和青少年的骨转换标志物。

Bone turnover markers in children and adolescents with environmentally determined short stature, living in the oil and gas processing region.

机构信息

Department of Children's Diseases No. 1 with Neonatology, West Kazakhstan Marat Ospanov Medical University, 030019, 68 Maresyev Str., Aktobe, Republic of Kazakhstan.

Department of Normal and Topographic Anatomy with Operative Surgery, West Kazakhstan Marat Ospanov Medical University, 030019, 68 Maresyev Str., Aktobe, Republic of Kazakhstan.

出版信息

Environ Sci Pollut Res Int. 2020 Sep;27(27):33998-34004. doi: 10.1007/s11356-020-09627-x. Epub 2020 Jun 15.

DOI:10.1007/s11356-020-09627-x
PMID:32557063
Abstract

In conditions of intensive development of gas fields, environmental safety issues are becoming increasingly important. High rates of gas production and growth of its chemical processing have turned gas industry enterprises into a powerful source of environmental pollution, which poses a real threat to public health and contributes to an increase in morbidities and environmentally determined pathological conditions. The development of methods for the diagnosis, treatment and prevention of such conditions is an important task for modern science. The aim of the research is to make a comprehensive assessment of serum markers of bone synthesis and resorption in children with short stature living in the oil and gas processing regions. A total of 240 children aged 8-17 years, living in the oil and gas processing region (Kenkiyak), and 409 schoolchildren (8-17 years old), living in the environmentally favourable region (Kobda village), during 3 years were examined. It was established that emissions of pollutants by oil processing enterprises account for almost 80% of all emissions into the atmosphere. Gas flaring at oil production sites plays a special role in this process. Speaking of the effects of environmental factors on children's health, it should be noted that there is no consensus on the mechanisms and consequences of exposure to low doses of chemical atmospheric pollutants in children and adolescents so far.

摘要

在天然气田大力开发的条件下,环境安全问题变得越来越重要。天然气产量的高增长率及其化学加工的增长,使天然气工业企业成为环境污染的强大源头,对公众健康构成了真正的威胁,并导致发病率和环境决定的病理状况增加。开发此类疾病的诊断、治疗和预防方法是现代科学的重要任务。本研究的目的是全面评估居住在油气加工区的身材矮小儿童的血清骨合成和骨吸收标志物。总共检查了 240 名年龄在 8-17 岁之间、居住在油气加工区(肯基亚克)的儿童和 409 名年龄在 8-17 岁之间、居住在环境有利区(科布达村)的学童,在 3 年内进行了检查。结果表明,石油加工企业的污染物排放量几乎占大气总排放量的 80%。在这个过程中,石油生产现场的天然气燃烧起着特殊的作用。谈到环境因素对儿童健康的影响,应该指出,迄今为止,对于儿童和青少年接触低剂量化学大气污染物的机制和后果,尚未达成共识。

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