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产后骨盆带疼痛和产后妊娠相关下腰痛的危险因素:系统评价和荟萃分析。

Risk factors for pelvic girdle pain postpartum and pregnancy related low back pain postpartum; a systematic review and meta-analysis.

机构信息

Physical Therapy Practice Fysi-Unique, Amersfoort, the Netherlands.

Physical Therapy Practice SaFyR, Rilland, the Netherlands.

出版信息

Musculoskelet Sci Pract. 2020 Aug;48:102154. doi: 10.1016/j.msksp.2020.102154. Epub 2020 May 5.

Abstract

BACKGROUND

Although pelvic girdle pain postpartum and pregnancy related low back pain postpartum (combined and named PGPP in this study) have a natural favourable course, there is a subgroup of women who have persistent complaints. The objective of this study was to identify personal-, (pre)pregnancy-, obstetric-, and child related risk factors on PGPP by means of a systematic literature review and meta-analysis.

METHODS

Literature searches of PubMed, EMBASE, CINAHL and Cochrane up to October 2018 were conducted. Prospective cohort studies in English or Dutch describing three or more risk factors for PGPP were included. We assessed articles for inclusion and risk of bias. Studies with high risk of bias were excluded from data extraction. Data was extracted and checked for accuracy confirming to the CHARMS-checklist. Homogeneous variables were pooled.

RESULTS

Twelve full text studies were assessed. Seven studies were excluded due to high risk of bias. Data was extracted from five studies. Multivariate analysis was not possible due to heterogeneity in included risk factors as well as outcome measures on risk factor per study. Pooled univariate significant risk factors on PGPP were: a history of low back pain, pre-pregnancy body mass index >25, pelvic girdle pain in pregnancy, depression in pregnancy, and a heavy workload in pregnancy. No significant obstetric and child related risk factors were reported.

CONCLUSIONS

Risk factors on PGPP have been identified. Since multivariate analysis was not possible the outcome should be treated with care, because interaction between risk factors could not be analysed.

摘要

背景

尽管产后骨盆带疼痛和产后妊娠相关下腰痛(在本研究中合称为 PGPP)具有自然的良好病程,但仍有一部分女性存在持续的疼痛。本研究旨在通过系统的文献回顾和荟萃分析,确定与 PGPP 相关的个人、(妊娠前)、产科和儿童相关的风险因素。

方法

对截至 2018 年 10 月的 PubMed、EMBASE、CINAHL 和 Cochrane 进行文献检索。纳入了描述 3 个或更多与 PGPP 相关风险因素的前瞻性队列研究,研究语言为英语或荷兰语。我们评估了纳入研究的文章和偏倚风险。高偏倚风险的研究被排除在数据提取之外。数据提取并根据 CHARMS 清单进行准确性检查。对同质变量进行了汇总。

结果

评估了 12 篇全文研究。由于高偏倚风险,有 7 项研究被排除。从 5 项研究中提取了数据。由于纳入的风险因素以及每项研究中风险因素的测量结果存在异质性,因此无法进行多变量分析。汇总的单变量 PGPP 显著风险因素为:下腰痛病史、妊娠前体重指数 >25、妊娠骨盆带疼痛、妊娠抑郁和妊娠期间工作量大。未报告与产科和儿童相关的显著风险因素。

结论

已经确定了 PGPP 的风险因素。由于无法进行多变量分析,因此应谨慎对待该结果,因为无法分析风险因素之间的相互作用。

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