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第十五届抗癫痫药物和设备试验会议记录:科学现状。

Proceedings of the 15th Antiepileptic Drug and Device Trials Meeting: State of the Science.

机构信息

Department of Neurology, New York University Langone Medical Center, New York, NY, USA.

Epilepsy Foundation, Landover, MD, USA.

出版信息

Epilepsy Behav. 2020 Oct;111:107189. doi: 10.1016/j.yebeh.2020.107189. Epub 2020 Jun 17.

Abstract

On May 22-24, 2019, the 15th Antiepileptic Drug and Device (AEDD) Trials Conference was held, which focused on current issues related to AEDD development from preclinical models to clinical prognostication. The conference featured regulatory agencies, academic laboratories, and healthcare companies involved in emerging epilepsy therapies and research. The program included discussions around funding and support for investigations in epilepsy and neurologic research, clinical trial design and integrated outcome measures for people with epilepsy, and drug development and upcoming disease-modifying therapies. Finally, the conference included updates from the preclinical, clinical, and device pipeline. Summaries of the talks are provided in this paper, with the various pipeline therapeutics in the listed tables to be outlined in a subsequent publication.

摘要

2019 年 5 月 22 日至 24 日,第 15 届抗癫痫药物和设备(AEDD)试验会议举行,会议重点关注从临床前模型到临床预后预测的 AEDD 开发相关的当前问题。会议的特点是监管机构、学术实验室和医疗保健公司参与新兴的癫痫治疗和研究。该计划包括围绕癫痫和神经研究调查的资金和支持、临床试验设计以及癫痫患者的综合结果测量、药物开发和即将出现的疾病修饰疗法进行讨论。最后,会议包括临床前、临床和设备管道的最新情况。本文提供了会谈摘要,并在列出的表格中列出了各种管道疗法,以便在后续出版物中进行概述。

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