Kennedy Melissa A
Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Room A205 VMC, 2407 River Drive, Knoxville, TN 37996-4543, USA.
Vet Clin North Am Small Anim Pract. 2020 Sep;50(5):1001-1011. doi: 10.1016/j.cvsm.2020.05.002. Epub 2020 Jun 17.
Feline infectious peritonitis (FIP) is a mysterious and lethal disease of cats. The causative agent, feline coronavirus (FCoV), is ubiquitous in most feline populations, yet the disease is sporadic in nature. Mutations in the infecting virus combined with an inappropriate immune response to the FCoV contribute to the development of FIP. Diagnosis can be challenging because signs may be vague, clinical pathology parameters are nonspecific, and the gold standard for diagnosis is invasive: histopathology of affected tissue. This article discusses the developments in the understanding of this disease as well as the progress in diagnosis and treatment.
猫传染性腹膜炎（FIP）是一种神秘且致命的猫科疾病。其病原体猫冠状病毒（FCoV）在大多数猫群中普遍存在，但该疾病本质上是散发性的。感染病毒的突变与对FCoV的不适当免疫反应共同导致了FIP的发展。诊断可能具有挑战性，因为症状可能模糊，临床病理参数不具特异性，且诊断的金标准具有侵入性：对受影响组织进行组织病理学检查。本文讨论了对该疾病认识的进展以及诊断和治疗方面的进步。
