[Burden of disease attributed to high level serum low-density lipoprotein cholesterol in China in 2017].

To quantitatively analyze the death and disability-adjusted life years (DALY) attributed to high level serum LDL-C in Chinese population in 2017. Data were obtained from the '2017 Global Burden of Disease Study (GBD2017)'. Population attributable fraction (PAF), number and rate of deaths and DALY attributable to high LDL-C were used to describe the burden of disease by gender, age groups, diseases and provinces in China. Both rates on mortality and DALY were standardized by GBD world population. In 2017, 862 759 deaths were caused by high level serum LDL-C in China, that accounting for 8.25 of the total deaths. Of the attributable deaths, 705 355 (81.76) persons died from ischemic heart disease (IHD), while the remaining 18.24 from ischemic stroke (IS). High LDL-C accounted for 40.30 of the total deaths from ischemic heart disease and 18.49 from ischemic stroke. The highest PAF of death (13.70) appeared in Jilin province and the lowest in Zhejiang province (4.65). PAF of death was seen higher in females than in males, while both age-standardized rates of mortality and DALY appeared higher in males than in females. High LDL-C attributed mortality rate appeared as 61.08/100 000 after standardization in Chinese population. High LDL-C attributed DALYs were 18.16 million person years, among which 76.76 were caused by IHD (13.94 million person years), with DALY rate as 1285.83/100 000. Among provinces, Heilongjiang showed the highest standardized DALY rate, and Zhejiang the lowest. The PAF, number of deaths, rates on mortality and DALY caused by high LDL-C were high among residents above 70 years old, with the DALY number as 8.56 million person years, highest seen in the age group from 50 to 69 years old. The burden of disease attributed to high level LDL-C was quite high and with gender, age group and interprovincial differences, in China in 2017.