伴有T细胞大颗粒淋巴细胞增殖（LGL）的骨髓增生异常综合征（MDS）的特征 - Suppr

Characterization of myelodysplastic syndromes (MDS) with T-cell large granular lymphocyte proliferations (LGL).

作者信息

Komrokji Rami S, Ali Najla Al, Sallman David, Padron Eric, Lancet Jeffrey, Sokol Lubomir, Varnadoe Christa, Burnette P K, List Alan

机构信息

Department of Malignant Hematology, H. Lee Moffitt Cancer center, Tampa, FL, USA.

Yale School of Nursing, New Haven, CT, USA.

出版信息

Leukemia. 2020 Nov;34(11):3097-3099. doi: 10.1038/s41375-020-0928-4. Epub 2020 Jun 21.

DOI:10.1038/s41375-020-0928-4

PMID:32565544

Abstract

摘要

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Characterization of myelodysplastic syndromes (MDS) with T-cell large granular lymphocyte proliferations (LGL).伴有T细胞大颗粒淋巴细胞增殖（LGL）的骨髓增生异常综合征（MDS）的特征

Leukemia. 2020 Nov;34(11):3097-3099. doi: 10.1038/s41375-020-0928-4. Epub 2020 Jun 21.

T-cell large granular lymphocyte proliferation in myelodysplastic syndromes: Clinicopathological features and prognostic significance.骨髓增生异常综合征中的T细胞大颗粒淋巴细胞增殖：临床病理特征及预后意义。

Leuk Res. 2016 Apr;43:18-23. doi: 10.1016/j.leukres.2016.02.006. Epub 2016 Feb 17.

A screening method with lymphocyte percentage and proportion of granular lymphocytes in the peripheral blood for large granular lymphocyte (LGL) leukemia.一种用于大颗粒淋巴细胞（LGL）白血病的外周血淋巴细胞百分比和颗粒淋巴细胞比例的筛查方法。

Int J Hematol. 2017 Jan;105(1):87-91. doi: 10.1007/s12185-016-2092-1. Epub 2016 Sep 29.

Clinical Features, Pathogenesis, and Treatment of Large Granular Lymphocyte Leukemias.大颗粒淋巴细胞白血病的临床特征、发病机制及治疗

Intern Med. 2017;56(14):1759-1769. doi: 10.2169/internalmedicine.56.8881. Epub 2017 Jul 15.

Comparison of T lymphocyte subsets in aplastic anemia and hypoplastic myelodysplastic syndromes.再生障碍性贫血与低增生性骨髓增生异常综合征中T淋巴细胞亚群的比较。

Life Sci. 2017 Nov 15;189:71-75. doi: 10.1016/j.lfs.2017.09.020. Epub 2017 Sep 19.

T-cell and natural killer-cell large granular lymphocyte leukemia neoplasias.T 细胞和自然杀伤细胞大颗粒淋巴细胞白血病肿瘤。

Leuk Lymphoma. 2011 Dec;52(12):2217-25. doi: 10.3109/10428194.2011.593276. Epub 2011 Jul 13.

T cell large granular lymphocyte leukemia associated with rheumatoid arthritis and neutropenia.与类风湿性关节炎和中性粒细胞减少症相关的T细胞大颗粒淋巴细胞白血病。

Clin Immunol. 2009 Aug;132(2):145-52. doi: 10.1016/j.clim.2009.03.515. Epub 2009 Apr 25.

Concurrent administration of darbepoetin alfa, cyclosporine A, and prednisolone is useful for T cell large granular lymphocyte leukemia associated with myelodysplastic syndrome complicated by Coombs-negative hemolytic anemia.同时给予达贝泊汀α、环孢素A和泼尼松龙对与骨髓增生异常综合征相关且并发库姆斯阴性溶血性贫血的T细胞大颗粒淋巴细胞白血病有效。

Ann Hematol. 2014 Nov;93(11):1937-9. doi: 10.1007/s00277-014-2075-3. Epub 2014 Apr 23.

Coincident myelodysplastic syndrome and T-cell large granular lymphocytic disease: clinical and pathophysiological features.同时存在的骨髓增生异常综合征和T细胞大颗粒淋巴细胞疾病：临床和病理生理特征

Br J Haematol. 2001 Jan;112(1):195-200. doi: 10.1046/j.1365-2141.2001.02561.x.

T-cell large granular lymphocyte leukemia associated with myelodysplastic syndrome: a clinicopathologic study of nine cases.与骨髓增生异常综合征相关的T细胞大颗粒淋巴细胞白血病：9例临床病理研究

Am J Clin Pathol. 2009 Mar;131(3):347-56. doi: 10.1309/AJCP6YHI1JEXAWAP.

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Clonal hematopoiesis in large granular lymphocytic leukemia.大颗粒淋巴细胞白血病中的克隆性造血

Leukemia. 2025 Feb;39(2):451-459. doi: 10.1038/s41375-024-02460-y. Epub 2024 Nov 21.

[Clinical characteristics of myeloid tumors combined with the proliferation of large granular lymphocytes].髓系肿瘤合并大颗粒淋巴细胞增殖的临床特征

Zhonghua Xue Ye Xue Za Zhi. 2024 Apr 14;45(4):396-400. doi: 10.3760/cma.j.cn121090-20231219-00327.

The constitutive activation of STAT3 gene and its mutations are at the crossroad between LGL leukemia and autoimmune disorders.STAT3 基因的组成性激活及其突变处于 LGL 白血病和自身免疫性疾病的交汇点。

Blood Cancer J. 2024 Jan 18;14(1):13. doi: 10.1038/s41408-024-00977-0.

Distinct mutational pattern of T-cell large granular lymphocyte leukemia combined with pure red cell aplasia: low mutational burden of STAT3.T 细胞大颗粒淋巴细胞白血病合并纯红细胞再生障碍性贫血的独特突变模式：STAT3 突变负担低。

Sci Rep. 2023 May 4;13(1):7280. doi: 10.1038/s41598-023-33928-z.

LGL Clonal Expansion and Unexplained Cytopenia: Two Clues Don't Make an Evidence.大颗粒淋巴细胞克隆性扩增与不明原因血细胞减少：两条线索并不构成证据。

Cancers (Basel). 2022 Oct 25;14(21):5236. doi: 10.3390/cancers14215236.

All that glitters is not LGL Leukemia.并非所有闪烁的都是 LGL 白血病。

Leukemia. 2022 Nov;36(11):2551-2557. doi: 10.1038/s41375-022-01695-x. Epub 2022 Sep 15.

Distinguishing STAT3/STAT5B-mutated large granular lymphocyte leukemia from myeloid neoplasms by genetic profiling.通过基因谱分析鉴别 STAT3/STAT5B 突变的大颗粒淋巴细胞白血病与髓系肿瘤

Blood Adv. 2023 Jan 10;7(1):40-45. doi: 10.1182/bloodadvances.2022008192.

Persistent Large Granular Lymphocyte Clonal Expansions: "The Root of Many Evils"-And of Some Goodness.持续性大颗粒淋巴细胞克隆性扩增：“万恶之源”——也是一些益处之源。

Cancers (Basel). 2022 Mar 5;14(5):1340. doi: 10.3390/cancers14051340.

Neutropenia and Large Granular Lymphocyte Leukemia: From Pathogenesis to Therapeutic Options.中性粒细胞减少症和大颗粒淋巴细胞白血病：从发病机制到治疗选择。

Cells. 2021 Oct 19;10(10):2800. doi: 10.3390/cells10102800.

Large Granular Lymphocyte Expansion in Myeloid Diseases and Bone Marrow Failure Syndromes: Whoever Seeks Finds.髓系疾病和骨髓衰竭综合征中的大颗粒淋巴细胞扩增：寻者得之。

Front Oncol. 2021 Oct 1;11:748610. doi: 10.3389/fonc.2021.748610. eCollection 2021.

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Characterization of myelodysplastic syndromes (MDS) with T-cell large granular lymphocyte proliferations (LGL).

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