Greatorex I F, Gibbs A C
Department of Community Medicine, University of Manchester Medical School.
J Epidemiol Community Health. 1988 Dec;42(4):365-9. doi: 10.1136/jech.42.4.365.
We identified 226 proximal femoral fractures prospectively in people aged over 60 years during one year in Stockport (population approximately 289,000). Our objective was to examine the association between primary treatment and outcome 6 months after the fracture using multivariate regression models. Higher haemoglobin concentrations and mental test scores on admission to hospital were associated with lower fatality within 6 months, whereas a high blood calcium-phosphate product, greater age, and an active medical problem at the time of the fracture were all associated with increased fatality. An intracapsular fracture, greater age, and a greater degree of dependency before the fracture all reduced the likelihood of regaining previous walking ability by 6 months. Good walking ability before the fracture increased the likelihood of walking well by 6 months. After adjusting for the effects of these extraneous variables there was no statistically significant association between treatment and outcome.
我们在斯托克波特（人口约28.9万）对60岁以上人群进行了为期一年的前瞻性研究，共识别出226例股骨近端骨折。我们的目的是使用多变量回归模型研究骨折后6个月时初始治疗与预后之间的关联。入院时较高的血红蛋白浓度和心理测试分数与6个月内较低的死亡率相关，而高血钙磷乘积、较大年龄以及骨折时存在的活动性医疗问题均与死亡率增加相关。囊内骨折、较大年龄以及骨折前较高的依赖程度均降低了6个月时恢复至骨折前行走能力的可能性。骨折前良好的行走能力增加了6个月时行走良好的可能性。在调整这些外部变量的影响后，治疗与预后之间无统计学显著关联。
