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埃塞俄比亚西南部吉马地区公共卫生设施中五岁以下儿童使用世卫组织救生药物的可得性和使用情况:一项横断面调查

Availability and Utilization of WHO Lifesaving Medicines for Children under Five in Public Health Facilities of the Jimma Zone, South West Ethiopia: A Cross-Sectional Survey.

作者信息

Tujo Tidenek Mulugeta, Gurmu Tadesse Gudeta

机构信息

School of Pharmacy, Institute of Health, Jimma University, Ethiopia.

出版信息

Int J Pediatr. 2020 May 31;2020:3505672. doi: 10.1155/2020/3505672. eCollection 2020.

Abstract

BACKGROUND

The increased morbidity and mortality rates in children under five in developing countries are mostly attributed to poor availability and failure of prescribing lifesaving medicines. This study was aimed at evaluating the availability and utilization of the WHO-recommended priority lifesaving medicines for children under five in public health facilities.

METHOD

A cross-sectional survey complemented with a qualitative method was conducted in 14 health centers and four hospitals in the Jimma Zone, Ethiopia. In the facilities, we assessed the availability within the last half year and on the day of the visit. Utilization of the medicines was assessed through a review of patient records of the last one year. Twelve in-depth interviews were carried out to collect the qualitative data, and the analysis was executed using thematic analysis.

RESULTS

For treatment of pneumonia, amoxicillin dispersible tablets and gentamycin injection were available in 94.4% of the facilities. For treatment of malaria, artemether/lumefantrine was available in 61.1% of the facilities. For pain management, paracetamol tablets were available in 94.4% of the facilities. AZT+3TC+NEV for HIV/AIDS management was available in all facilities. At least one essential medicine was out of stock in the past six months with the average duration of 33.6 days in health centers and 28.25 days in hospitals. Oral rehydration salt and zinc (84.7%) and AZT+3TC+NEV (100%) had better utilization. However, for almost all cases, other nonpriority medicines were highly prescribed. Lack of administrative commitment, supply of near expiry products, complexity of diseases, and lack of customized child formulations were among the challenges of availability and utilization of those medicines.

CONCLUSIONS

The overall availability of lifesaving medicines on the day of the visit was fairly good but with poor utilization in almost all facilities. Some products were not available for considerable length of time in the past six months.

摘要

背景

发展中国家五岁以下儿童发病率和死亡率上升,主要归因于救命药物供应不足和处方不当。本研究旨在评估公共卫生机构中世界卫生组织推荐的五岁以下儿童优先救命药物的供应情况和使用情况。

方法

在埃塞俄比亚吉马地区的14个卫生中心和4家医院进行了一项横断面调查,并辅以定性方法。在这些机构中,我们评估了过去半年内以及访视当天的药品供应情况。通过回顾过去一年的患者记录来评估药品的使用情况。进行了12次深入访谈以收集定性数据,并采用主题分析法进行分析。

结果

用于治疗肺炎的阿莫西林分散片和庆大霉素注射液在94.4%的机构中有供应。用于治疗疟疾的蒿甲醚/本芴醇在61.1%的机构中有供应。用于疼痛管理的对乙酰氨基酚片在94.4%的机构中有供应。用于艾滋病毒/艾滋病管理的齐多夫定+拉米夫定+奈韦拉平在所有机构中均有供应。在过去六个月中,至少有一种基本药物缺货,卫生中心的平均缺货时长为33.6天,医院为28.25天。口服补液盐和锌(84.7%)以及齐多夫定+拉米夫定+奈韦拉平(100%)的使用率较高。然而,几乎在所有情况下,其他非优先药物的处方量都很高。缺乏行政承诺、供应临近过期的产品、疾病的复杂性以及缺乏定制的儿童制剂是这些药物供应和使用面临的挑战。

结论

访视当天救命药物的总体供应情况相当不错,但几乎所有机构的使用率都很低。在过去六个月中,一些产品在相当长的时间内都无法供应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01c1/7285402/d1459f831d18/IJPEDI2020-3505672.001.jpg

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