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溶菌酶在人支气管腺中的超微结构免疫细胞化学定位

Ultrastructural immunocytochemical localisation of lysozyme in human bronchial glands.

作者信息

Bowes D, Corrin B

出版信息

Thorax. 1977 Apr;32(2):163-70. doi: 10.1136/thx.32.2.163.

DOI:10.1136/thx.32.2.163
PMID:325682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC470556/
Abstract

An immunocytochemical unlabelled antibody method using rabbit antihuman lysozyme, antirabbit immunoglobulin, and soluble rabbit antihorseradish peroxidase/horseradish peroxidase complexes was used to study the fine structural distribution of lysozyme in human bronchial glands. None was identified in mucous cells but there was heavy staining of the serous cell granules. The serous cell granules were not stained uniformly, suggesting the presence of other secretory products but lysozyme secretion appears to be a major function of these cells. The pathological implications of this are discussed.

摘要

采用兔抗人溶菌酶、抗兔免疫球蛋白以及可溶性兔抗辣根过氧化物酶/辣根过氧化物酶复合物的免疫细胞化学未标记抗体法，研究人支气管腺中溶菌酶的精细结构分布。黏液细胞中未发现溶菌酶，但浆液细胞颗粒有重度染色。浆液细胞颗粒染色不均匀，提示存在其他分泌产物，但溶菌酶分泌似乎是这些细胞的主要功能。文中讨论了其病理学意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/dc438ed34d68/thorax00152-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/c47374153c21/thorax00152-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/be3e6f56dc7f/thorax00152-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/08461c8cdd3d/thorax00152-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/b27ee84c1515/thorax00152-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/c41c9c5ed2b3/thorax00152-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/58abc00e9b2d/thorax00152-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/dc438ed34d68/thorax00152-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/c47374153c21/thorax00152-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/be3e6f56dc7f/thorax00152-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/08461c8cdd3d/thorax00152-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/b27ee84c1515/thorax00152-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/c41c9c5ed2b3/thorax00152-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/58abc00e9b2d/thorax00152-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8906/470556/dc438ed34d68/thorax00152-0050-a.jpg

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