体力活动、久坐行为与结直肠癌患者尿氧化鸟嘌呤的相关性：ColoCare 研究结果。
Associations between physical activity, sedentary behavior, and urinary oxidized guanine in colorectal cancer patients: results from the ColoCare Study.
机构信息
Huntsman Cancer Institute, Salt Lake City, UT 84112, USA.
Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg 69120, Germany.
出版信息
Appl Physiol Nutr Metab. 2020 Nov;45(11):1306-1309. doi: 10.1139/apnm-2019-0836. Epub 2020 Jun 22.
Abstract
To determine associations between physical activity (PA), sedentary behavior (SB), and oxidative stress in colorectal cancer patients, ColoCare Study participants in Germany wore an accelerometer 6 and/or 12 months after surgery. Spearman partial correlations were used to assess associations between PA and urinary concentrations of oxidized guanine, a validated marker of oxidative stress. There were no significant associations between PA or SB and oxidized guanine in = 76 measurements (ng/mg creatinine; = 0.03, = 0.76 for PA, = -0.05, = 0.69 for SB). Objectively measured PA was not associated with a marker of oxidative stress in colorectal cancer patients.
摘要
为了确定体力活动（PA）、久坐行为（SB）与结直肠癌患者氧化应激之间的关联，德国 ColoCare 研究的参与者在手术后 6 个月和/或 12 个月佩戴了加速度计。采用斯皮尔曼偏相关分析评估 PA 与尿中氧化鸟嘌呤浓度之间的相关性，氧化鸟嘌呤是氧化应激的一个经过验证的标志物。在 76 次测量中（ng/mg 肌酐），PA 或 SB 与氧化鸟嘌呤之间没有显著关联（PA： = 0.03， = 0.76；SB： = -0.05， = 0.69）。在结直肠癌患者中，客观测量的 PA 与氧化应激标志物无关。
相似文献
1
Associations between physical activity, sedentary behavior, and urinary oxidized guanine in colorectal cancer patients: results from the ColoCare Study.体力活动、久坐行为与结直肠癌患者尿氧化鸟嘌呤的相关性：ColoCare 研究结果。
Appl Physiol Nutr Metab. 2020 Nov;45(11):1306-1309. doi: 10.1139/apnm-2019-0836. Epub 2020 Jun 22.
2
Accelerometer-Measured Sedentary and Physical Activity Time and Their Correlates in European Older Adults: The SITLESS Study.使用加速度计测量的欧洲老年人的久坐时间和身体活动时间及其相关性：SITLESS 研究。
J Gerontol A Biol Sci Med Sci. 2020 Sep 16;75(9):1754-1762. doi: 10.1093/gerona/glaa016.
3
Physical Activity and Sedentary Behavior of Children in Afterschool Programs: An Accelerometer-Based Analysis in Full-Day and Half-Day Elementary Schools in Germany.课后活动项目中儿童的身体活动与久坐行为：基于加速度计对德国全日制和半日制小学的分析
Front Public Health. 2020 Sep 2;8:463. doi: 10.3389/fpubh.2020.00463. eCollection 2020.
4
Objectively Measured Changes in Physical Activity and Sedentary Behavior in Cardiac Rehabilitation: A PROSPECTIVE COHORT STUDY.客观测量的心脏康复中体力活动和久坐行为的变化：一项前瞻性队列研究。
J Cardiopulm Rehabil Prev. 2018 Nov;38(6):E5-E8. doi: 10.1097/HCR.0000000000000334.
5
Association of Physical Activity, Sedentary Behavior, and Sleep With Unhealthy Aging: Consistent Results for Device-Measured and Self-reported Behaviors Using Isotemporal Substitution Models.身体活动、久坐行为和睡眠与不健康衰老的关联：使用等时替代模型的设备测量和自我报告行为的一致结果。
J Gerontol A Biol Sci Med Sci. 2021 Jan 1;76(1):85-94. doi: 10.1093/gerona/glaa177.
6
Comparison of self-report versus accelerometer - measured physical activity and sedentary behaviors and their association with body composition in Latin American countries.比较自我报告与加速度计测量的身体活动和久坐行为及其与拉丁美洲国家身体成分的关系。
PLoS One. 2020 Apr 28;15(4):e0232420. doi: 10.1371/journal.pone.0232420. eCollection 2020.
7
Plasma 25-Hydroxyvitamin D Levels in Colorectal Cancer Patients and Associations with Physical Activity.结直肠癌患者的血浆25-羟基维生素D水平及其与身体活动的关联
Nutr Cancer. 2017 Feb-Mar;69(2):229-237. doi: 10.1080/01635581.2017.1265131. Epub 2017 Jan 17.
8
Associations of older adults' excursions from home with health-related physical activity and sedentary behavior.老年人离家外出活动与与健康相关的体力活动和久坐行为的关联。
Arch Gerontol Geriatr. 2021 Jan-Feb;92:104276. doi: 10.1016/j.archger.2020.104276. Epub 2020 Oct 1.
9
Accelerometry-measured physical activity and sedentary behaviour of preschoolers in Nova Scotia, Canada.加拿大新斯科舍省学龄前儿童的加速度计测量体力活动和久坐行为。
Appl Physiol Nutr Metab. 2019 Sep;44(9):1005-1011. doi: 10.1139/apnm-2018-0683. Epub 2019 Feb 7.
10
Objectively measured sedentary behavior and physical activity in a sample of Finnish adults: a cross-sectional study.芬兰成年人样本中客观测量的久坐行为和身体活动：一项横断面研究。
BMC Public Health. 2016 Sep 1;16(1):920. doi: 10.1186/s12889-016-3591-y.
引用本文的文献
1
Sedentary behavior and physical activity one year after colorectal cancer diagnosis: results from the ColoCare Study.结直肠癌诊断一年后的久坐行为与身体活动：ColoCare研究结果
J Cancer Surviv. 2025 Feb 22. doi: 10.1007/s11764-025-01756-x.
本文引用的文献
1
The ColoCare Study: A Paradigm of Transdisciplinary Science in Colorectal Cancer Outcomes.ColoCare 研究：结直肠癌结局转化医学研究的范例。
Cancer Epidemiol Biomarkers Prev. 2019 Mar;28(3):591-601. doi: 10.1158/1055-9965.EPI-18-0773. Epub 2018 Dec 6.
2
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms.能量平衡与胃肠道癌症：风险、干预、结果与机制。
Nat Rev Gastroenterol Hepatol. 2018 Nov;15(11):683-698. doi: 10.1038/s41575-018-0053-2.
3
The association between recreational physical activity, sedentary time, and colorectal polyps in a population screened for colorectal cancer.在接受结直肠癌筛查的人群中，休闲体育活动、久坐时间与结直肠息肉之间的关联。
Cancer Epidemiol. 2018 Apr;53:12-20. doi: 10.1016/j.canep.2017.12.017. Epub 2018 Jan 30.
4
Lifestyle after Colorectal Cancer Diagnosis in Relation to Survival and Recurrence: A Review of the Literature.结直肠癌诊断后的生活方式与生存及复发的关系：文献综述
Curr Colorectal Cancer Rep. 2017;13(5):370-401. doi: 10.1007/s11888-017-0386-1. Epub 2017 Sep 14.
5
Colorectal cancer statistics, 2017.结直肠癌统计数据，2017 年。
CA Cancer J Clin. 2017 May 6;67(3):177-193. doi: 10.3322/caac.21395. Epub 2017 Mar 1.
6
Physical Activity and Sedentary Behavior in Breast and Colon Cancer Survivors Relative to Adults Without Cancer.乳腺癌和结肠癌幸存者与无癌症成年人相比的身体活动和久坐行为
Mayo Clin Proc. 2017 Mar;92(3):391-398. doi: 10.1016/j.mayocp.2016.12.015. Epub 2017 Feb 6.
7
Plasma 25-Hydroxyvitamin D Levels in Colorectal Cancer Patients and Associations with Physical Activity.结直肠癌患者的血浆25-羟基维生素D水平及其与身体活动的关联
Nutr Cancer. 2017 Feb-Mar;69(2):229-237. doi: 10.1080/01635581.2017.1265131. Epub 2017 Jan 17.
8
9
Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors.结直肠癌幸存者久坐时间及其累积模式与健康相关生活质量的关联。
Prev Med Rep. 2016 Jul 1;4:262-9. doi: 10.1016/j.pmedr.2016.06.022. eCollection 2016 Dec.
10
Patterns and correlates of accelerometer-assessed physical activity and sedentary time among colon cancer survivors.结肠癌幸存者中通过加速度计评估的身体活动和久坐时间的模式及相关因素。
Cancer Causes Control. 2016 Jan;27(1):59-68. doi: 10.1007/s10552-015-0683-4. Epub 2015 Oct 30.
Zotero 插件