Zhong Yiping, Huang Lining, Chen Yongjun, Yan Tingting, Yang Bin, Man Mao-Qiang
Aesthetic Department, Dermatology Hospital, Southern Medical University, Guangzhou, China.
J Cosmet Dermatol. 2021 Feb;20(2):466-471. doi: 10.1111/jocd.13558. Epub 2020 Aug 29.
Becker's nevus is a common skin disorder. Lasers and light instruments are the major modalities for the treatment of Becker's nevus, but the outcomes were mixed.
To evaluate the efficacy of the intense pulsed light for Becker's nevus in a large Chinese cohort.
We retrospectively analyzed the efficacy of the intense pulsed light for Becker's nevus in a single center.
A total of 45 patients, including 26 males and 19 females (male to female ratio = 1.4), aged 5-42 years, were included in this analysis. Twenty-seven patients (60%) were with hypertrichosis. Treatments with intense pulsed light resulted in over 75% improvements in pigmentation and hair density in 1 and 2 cases, respectively. One patient displayed 51%-75% reductions in hair density. The rest displayed ≤50% improvements in pigmentation and hair density. Recurrence occurred in all cases within 6 months after the last treatment. Adverse reactions were temporary and mild hypopigmentation, hyperpigmentation, hypertrophic scar, pain, and erythema.
Intense pulsed light does not exhibit long-term benefits for Becker's nevus. Further studies in the large cohort are still required to validate the present results. Moreover, whether changes in the treatment parameters can improve the efficacy of intense pulsed light remains to be explored.
贝克痣是一种常见的皮肤疾病。激光和光仪器是治疗贝克痣的主要方式,但治疗效果不一。
评估强脉冲光治疗中国一大群患者贝克痣的疗效。
我们回顾性分析了单中心应用强脉冲光治疗贝克痣的疗效。
本分析共纳入45例患者,其中男性26例,女性19例(男女比例=1.4),年龄5 - 42岁。27例患者(60%)有多毛症。强脉冲光治疗后,分别有1例和2例患者色素沉着和毛发密度改善超过75%。1例患者毛发密度降低51% - 75%。其余患者色素沉着和毛发密度改善≤50%。所有病例在最后一次治疗后6个月内均复发。不良反应为暂时性,包括轻度色素减退、色素沉着、肥厚性瘢痕、疼痛和红斑。
强脉冲光对贝克痣无长期疗效。仍需在更大队列中进行进一步研究以验证本结果。此外,治疗参数的改变是否能提高强脉冲光的疗效仍有待探索。