Aesthetic Department, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Dermatology Services, Department of Dermatology, University of California San Francisco and Veterans Affairs Medical Center, San Francisco, CA, 94121, USA.
Lasers Med Sci. 2019 Aug;34(6):1071-1079. doi: 10.1007/s10103-019-02734-3. Epub 2019 Feb 14.
Becker's nevus is a common pigmented dermatosis, usually featured by ipsilateral pigmented patch with hypertrichosis. Becker's nevus is often treated with various types of lasers although other regimens are available. However, clinical outcomes appear inconsistent among studies. To summarize the clinical outcomes of Becker's nevus treated with lasers via literature review. A variety of lasers had been used alone or in combination to treat Becker's nevus. Laser wavelengths used for Becker's nevus ranged from 504 to 10,600 nm, while the number of treatment varied from 1 to 12 sessions. The clinical outcomes were mixed although combination of lasers with different wavelengths appeared to achieve a better efficacy. Adverse effects were usually mild to moderate erythema. While lasers are relatively safe, their efficacy for Becker's nevus is moderate. It seems that combination therapy could improve the outcome. However, trials in larger group of patients are required to validate the efficacy of each type of lasers for Becker's nevus.
贝克痣是一种常见的色素性皮肤疾病,通常表现为同侧色素斑伴多毛症。贝克痣可以通过各种类型的激光进行治疗,尽管还有其他的治疗方案。然而,临床结果在不同的研究中似乎并不一致。通过文献回顾总结激光治疗贝克痣的临床结果。已经有多种激光单独或联合用于治疗贝克痣。用于治疗贝克痣的激光波长范围从 504nm 到 10600nm,而治疗次数从 1 次到 12 次不等。虽然联合使用不同波长的激光似乎可以提高疗效,但临床结果参差不齐。不良反应通常为轻度至中度红斑。虽然激光治疗相对安全,但治疗贝克痣的疗效中等。联合治疗可能会改善治疗效果。然而,需要更大规模的患者临床试验来验证每种激光治疗贝克痣的疗效。