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特发性肺含铁血黄素沉着症肺移植后的疾病复发

Disease recurrence after lung transplantation for idiopathic pulmonary hemosiderosis.

作者信息

Ross Bryan, Halloran Kieran, Adam Benjamin, Laing Bryce, Hirji Alim

机构信息

Department of Medicine, University of Alberta, Edmonton, Canada.

Department of Medicine, McGill University, Montreal, Canada.

出版信息

Respir Med Case Rep. 2020 Jun 10;30:101128. doi: 10.1016/j.rmcr.2020.101128. eCollection 2020.

Abstract

Idiopathic pulmonary hemosiderosis is characterized by the triad of hemoptysis, iron deficiency anemia and pulmonary infiltrates. Though idiopathic pulmonary hemosiderosis has classically been described as a childhood disease, survival into adulthood is possible. Treatment options for advanced and/or refractory disease is limited, and in our unique case of idiopathic pulmonary hemosiderosis with precapillary pulmonary hypertension, lung transplantation has had a favorable short-term outcome. We also demonstrate that disease recurrence of idiopathic pulmonary hemosiderosis following lung transplantation is possible.

摘要

特发性肺含铁血黄素沉着症的特征为咯血、缺铁性贫血和肺部浸润三联征。尽管特发性肺含铁血黄素沉着症传统上被描述为一种儿童疾病,但也有可能存活至成年。晚期和/或难治性疾病的治疗选择有限,在我们这个特发性肺含铁血黄素沉着症合并毛细血管前性肺动脉高压的独特病例中,肺移植取得了良好的短期效果。我们还证明了肺移植后特发性肺含铁血黄素沉着症疾病复发是有可能的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bc9/7305376/f7710ab51900/gr1.jpg

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