Department of Urology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Department of Urology, Putuo People's Hospital of Tongji University, Shanghai, China.
Ann Clin Lab Sci. 2020 May;50(3):391-396.
Myoepithelial carcinoma (MC), also known as malignant myoepithelial neoplasm, is more common in the parotid glands of the head and neck. The main clinical manifestation is the growth of a nonspecific, painless mass at the primary site. We report the first case of MC derived from the epididymis. The current reports of non-parotid MC are still rare, and epididymal-derived MC has not been reported previously. Simultaneously, we explore the role of EWSR1 fusion as a predicting marker and further reveal the origin of MC to provide new ideas for its diagnosis and treatment.
肌上皮癌（MC），又称恶性肌上皮瘤，多见于头颈部的腮腺。主要临床表现为原发部位出现无特异性、无痛性肿块。我们报告首例源于附睾的 MC。目前，非腮腺 MC 的报道仍较少，附睾来源的 MC 此前尚未报道。同时，我们探讨了 EWSR1 融合作为预测标志物的作用，并进一步揭示了 MC 的起源，为其诊断和治疗提供了新的思路。
