用于检测新型冠状病毒的唾液聚合酶链反应检测
Saliva-based PCR tests for SARS-CoV-2 detection.
作者信息
Takeuchi Yoshimasa, Furuchi Mika, Kamimoto Atsushi, Honda Kazuya, Matsumura Hideo, Kobayashi Ryutaro
机构信息
Department of Comprehensive Dentistry and Clinical Education, Nihon University School of Dentistry.
Division of Dental Education, Dental Research Center, Nihon University School of Dentistry.
出版信息
J Oral Sci. 2020;62(3):350-351. doi: 10.2334/josnusd.20-0267.
The outbreak of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. Nasopharyngeal swabs are widely used in polymerase chain reaction (PCR) test to detect SARS-CoV-2. However, the collection of nasopharyngeal swabs has a series of drawbacks concerning exposure of healthcare staff, difficulty in collection, and discomfort of patients. Therefore, an alternative noninvasive sample for diagnostic of emerging viral diseases is required. The usefulness of saliva screening tests is compared to conventional swab tests in this report. The results suggest that saliva could be a reliable sample for detecting SARS-CoV-2.
由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019年新型冠状病毒病（COVID-19）疫情已在全球蔓延。鼻咽拭子广泛用于聚合酶链反应（PCR）检测以检测SARS-CoV-2。然而，鼻咽拭子的采集存在一系列缺点，包括医护人员暴露风险、采集困难以及患者不适等问题。因此，需要一种用于诊断新发病毒性疾病的替代性非侵入性样本。本报告比较了唾液筛查检测与传统拭子检测的效用。结果表明，唾液可能是检测SARS-CoV-2的可靠样本。
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