Khadka Sujan, Proshad Ram, Thapa Alina, Acharya Krishna Prasad, Kormoker Tapos
Department of Microbiology, Birendra Multiple Campus, Tribhuvan University, Bharatpur, Chitwan 44200 Nepal.
State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085 China.
Trop Med Health. 2020 Jun 22;48:50. doi: 10.1186/s41182-020-00237-4. eCollection 2020.
Dengue, a mosquito-borne viral infectious disease, causes a high morbidity and mortality in tropical and subtropical areas of the world. In Nepal, the first case of dengue was reported in 2004 followed by frequent outbreaks in subsequent years, with the largest being in 2019 taking the death toll of six. It is reported that the number of dengue fever cases are soaring in Nepal spreading from the plains to more hilly regions. This might have serious public health implications in the future when combined with other factors, such as: global warming, lack of early detection and treatment of dengue, lack of diagnostic facilities, poor healthcare systems and mosquito control strategies. Nepal, thus, needs a cost-effective mosquito control strategy for the prevention and control of dengue. The -mediated biological method of the dengue control strategy is novel, economic, and environment-friendly. It has been successfully trialed in several areas of dengue-prone countries of the world, including Australia, Malaysia, Vietnam etc. resulting in significant reductions in dengue incidence. Given the lack of effective vector control strategy and weak economic condition of the country along with the persistence of climate and environment conditions that favors the host ( mosquito) for , this approach can be a promising option to control dengue in Nepal.
登革热是一种由蚊子传播的病毒性传染病,在世界热带和亚热带地区导致高发病率和死亡率。在尼泊尔,2004年报告了首例登革热病例,随后几年频繁爆发,2019年爆发规模最大,造成6人死亡。据报道,尼泊尔登革热病例数正在飙升,从平原地区蔓延到更多山区。未来,当与其他因素结合时,这可能会对公共卫生产生严重影响,这些因素包括:全球变暖、登革热缺乏早期检测和治疗、缺乏诊断设施、医疗系统薄弱以及蚊虫控制策略不力。因此,尼泊尔需要一种具有成本效益的蚊虫控制策略来预防和控制登革热。登革热控制策略的介导生物方法新颖、经济且环保。它已在世界上一些登革热高发国家的多个地区成功试验,包括澳大利亚、马来西亚、越南等,登革热发病率显著降低。鉴于该国缺乏有效的病媒控制策略、经济状况薄弱以及有利于宿主(蚊子)生存的气候和环境条件持续存在,这种方法可能是尼泊尔控制登革热的一个有前景的选择。